Introduction to signalling molecules Flashcards
thing in common with all signalling molecules is that
they bind to specific/complementary receports on their target cells
signalling molecules are aka
ligands
describe types of forms of signals (physical etc)
chemical (Eg. signalling molecules), mechanical (touch/pressure like pressure receptors in joints), electromagnetic (like photoreceptors in the eyes)
signalling molecules have varying chemical structurs, being made of
aa’s pp’s peptides, proteins
also have
varying sizes, water affinities, functions (neurotransmitters, cytokines)
signalling molecules can be grouped
in how far they ahve to go to exert effect on target cells.
define: endocrine signalling
: secreted directly into circulatory system and distributed widely throughout the body (hormones)
define: paracrine singalling
signals move by diffusion through interstitial fluid to nearby cells
define: autocrine signalling
secreted from cell that receives the signal (eg. T cells)
define: contact dependent signalling
: signals move from the cytosol of one cell to that of another due to structural features
strcutral features enabling contact dependent signalling?
gap junctions (in animal cells, protein lined pores in the plasma membrane, enabling small molecules and electrical signals to pass) and plasmodesmata (equivalent in plants)