cytokenes Flashcards
define: cytokenes
cell signalling molecuels that do cell-to cell communication in immune responses and stimulate movement of cells towards sites of inflammation, infection and trauma
chemical structures?
• Many peptides, some proteins/glycoproteins
where are cytokenes secreted
mainly by mamalian immune cells
effects?
stimulatory/inhibitory/regulatory
can be chemical _____ or chemical ______
mediators (enhance/activate function of other proteins) or modulators (directly influence other molecules) f
can same cytokenes produce different responeses in different cells?
yes
cytokenes usually act….
briefly, locally and at low concentrations
describe signal tranduction
• Released from signalling cell and diffuse to nearby target cells, bind to receptor, signal transduction occurs (cytokenes related genes are switched on/off) and responses occur