immune deficiency diseases Flashcards

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1
Q

define: immune deficiency disease

A

malfunction on one or more components of the immune system; can be inherited/developed due to anothwe disease

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2
Q

describe how human immunodeficiency virus is structured

A

retrovirus (contains RNA - in this case 2 single stranded fragments)

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3
Q

how does HIV enter cells and do its thing

A

glycoproteins bind to CD4 receptors on helper t cells, RNA replicates (reverse transcriptase turns RNA to DNA which embeds itself into cell genes, producing viral proteins needed to make new viruses)

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4
Q

why to helper t cell count divide

A

virus changes antigens and recognised by cytotoxic t cells as being non self so is attacked

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5
Q

effect of low helper t cell count

A

helper t cells are needed ot stimulate b cells and cytotoxic t cells, so less immunity = opportunistic disease more likely

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6
Q

how is HIV controlled

A

drugs to prevent action of reverse transcriptase

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