Introduction to Oncology & Cancer Biology

Question 1

What are some potential causes of cancer

Answer 1

lifestyle habits
genetics
chemical carcinogens
ionizing or UV radiation
Viruses, bacteria or parasites
environmental factors

Question 2

Understand multi-step carcinogenesis

Question 3

Understand the Hallmarks of Cancer

Question 4

What are some more common causes of cancer in urban environments?

Answer 4

lymphoma, nasal carcinoma, tonsillar squamous cell Carcinoma

Question 5

Where does radiation exposure commonly cause exposure?

Answer 5

UV: nasal planum and cutaneous squamous cell Carcinoma
Ionizing: sarcoma development in sites of previous radiation tx

Question 6

What has caused an increase in incidence of bladder cancer?

Answer 6

topical insecticides and dips, especially in overweight dogs
-newer spot on topical flea and tick products haven’t caused it

Question 7

What breeds have an increased rate of transitional cell carcinoma? (bladder cancer)

Answer 7

scotties, shelties, beagles

Question 8

What are the three stages of multi-step carcinogenesis?

Answer 8

initiation, promotion and progression

Question 9

What is initiation in regards to carcinogenesis ?

Answer 9

interaction of the carcinogen with cellular DNA in an individual cell

Question 10

Is an initiated cell a cancer cell?

Answer 10

No not a cancer cell bc it doesn’t have autonomous growth ability. only considered cancerous until all steps of carcinogenesis occurs.