Introduction to Hematology Flashcards
Hematology comes from the Greek words _____ which means “blood” and _____ which means “study of”
Haima
Logos
Haima means ____
Blood
Logos means _____
Study of
Study of the quality and quantity of the cellular elements of the peripheral blood and the bone marrow which includes erythrocytes (RBC), leukocytes (WBC), and thrombocytes (Platelets).
Hematology
Study of the disorders and abnormalities related or associated with the quality and quantity of the cellular elements of the blood.
Hematology
Study of laboratory procedures and techniques being used to examine the quality and quantity of the cellular elements of the blood.
Hematology
First scientist who described “worms” in the blood in 1657.
Athanasius Kircher
Athanasius Kircher is the first scientist who described _____ in what year?
“worms” in blood
1657
Gave an account for RBC in 1674.
Anton van Leeuwenhoek
Anton van Leeuwenoek gave an account for _____ in what year
Gave an account for RBC
1674
A scientist that describes platelets in 1800.
Guilio Bizzozero
Guilio Bizzozero describes _____ in what year?
Platelets
1800
Who developed the Wright Stain in 1902?
James Homer Wright
James Homer Wright develops _____ in what year?
Wright Stain
1902
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
A/An
Without
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
Aniso
Unequal/Dissimilar
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
Cyt
Cell
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
Dys
Abnormal/Difficult
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
Erythro
Red
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
Ferro/Ferr
Iron
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
Hypo
Deficient/Decreased
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
Hemo (Hemato)
Pertains to Blood
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
Hyper
Beyond/Increase/Extreme
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
Iso
Equal/Alike
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
Leuko
White
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
Macro
Large
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
Mega
Very Large/Huge
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
Micro
Small
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
Myelo
From the Bone Marrow
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
Pan
All/Overall
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
Phleb
Vein
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
Phago
Eat/Digest
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
Poikilo
Varied/Irregular
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
Poly
Many
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
Schis
Split
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
Scler
Hard
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
Spleen
Spleen
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
Throm (o)
Clot/Thrombus
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
Xanth
Yellow
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
-oid
Like
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
-osis
Increased
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
Pan
All
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
-penia
Decreased
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
Plasia
Formation
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
Poeisis
Cell Production
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
Poly
Many
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
Pro
Before
Give the meaning of the Common Prefixes and Suffixes from Greek And Latin that is used in Hematology:
Thrombo
Clot
Quality pertains to the _____ of the cells
Morphology
Quantity pertains to the _____ of the cells
Number
_____ pertains to the morphology of the cells
Quality
_____ pertains to the number of the cells
Quantity
Responsible for blood coagulation
Thrombocytes
_____ and _____ does not have nucleus
RBC
Platelets
_____ does not have hemoglobin
Leukocytes
Give the meaning of the following abbreviations:
Hct
Hematocrit
Give the meaning of the following abbreviations:
Hb/Hgb
Hemoglobin
Give the meaning of the following abbreviations:
CBC
Complete Blood Count
Give the meaning of the following abbreviations:
MCV
Mean Corposcular Volume
Give the meaning of the following abbreviations:
MCH
Mean Corposcular Hemoglobin
Give the meaning of the following abbreviations:
MCHC
Mean Corposcular Hemoglobin Concentration
What are included in the Blood Indices?
MCV
MCH
MCHC
Used to identify the type of Anemia
Blood Indices
Old Unit of Hemoglobin
g/100ml (g%)
Old Unit of Cells:
Per cumm
Old Unit of MCH:
Uug
SI Unit of Hemoglobin:
g/L
SI Unit of Cells:
Per uL or cells/L
SI Unit of MCH:
pG
SI Unit of MCV:
fl
It is the vital life-sustaining fluid circulating constantly in a closed system of blood vessels
Blood
Circulation of Blood (paths of the blood when it is pumped)
Blood is pumped from the heart into arteries, from arteries into the capillaries and from the capillaries into veins then it returns to the heart.
2 Main Composition of Blood:
Whole Blood
Liquid
Whole Blood is composed of:
Erythrocytes
Leukocytes
Platelets/Thrombocytes
Liquid Portion of the Blood is composed of:
Plasma
Serum
Liquid potion of unclotted blood.
Plasma
Fluid that remains after coagulations
has occurred and clot has formed.
Serum
Liquid portion of clotted blood.
Serum
It is the anucleate, biconcave, discoid cells filled with reddish protein.
Erythrocytes (RBC)
Reddish protein is also known as the _____
Hemoglobin
Responsible for giving color to the RBC
Hemoglobin
Color of the Erythrocytes
Salmon Pink
Size of the Erythrocytes
7-8 um in diameter with central pallor
A cellular component of the blood that lacks hemoglobin, has a nucleus, is capable of motility, and defends the body against infection and disease by ingesting foreign materials and cellular debris by destroying infectious agents or by producing antibodies.
Leukocytes (WBC)
2 Classifications of Leukocytes:
Phagocytes
Immunocytes
Phagocytes includes:
Neutrophils
Monocytes
Immunocytes includes:
Lymphocytes
Are true blood cells that maintain blood vessels integrity by initiating vessel repairs.
Thrombocytes (Platelets)
Size of Thrombocytes:
2-4 um in diameter
Platelets came from _____ which is the largest cell in the bone marrow
Megakaryocytes
Largest cell in the bone marrow
Megakaryocytes
Give the relative size of the formed elements:
Thrombocytes
2-4 um
Give the relative size of the formed elements:
Erythrocytes
7-8 um
Give the relative size of the formed elements:
Normal Lymphocytes
6-9 um
Give the relative size of the formed elements:
Reactive Lymphocytes
10-22 um
Give the relative size of the formed elements:
Basophils
10-15 um
Give the relative size of the formed elements:
Segmented Neutrophils
10-15 um
Give the relative size of the formed elements:
Band Neutrophils
10-15 um
Give the relative size of the formed elements:
Eosinophils
12-16 um
Give the relative size of the formed elements:
Monocytes
12-20 um
It is the largest among the formed elements.
Monocytes
It is the smallest among the formed elements.
Platelets/Thrombocytes
This is seen in between the Plasma and the Red Blood Cells.
Buffy Coat
Percentage of plasma in the blood
55%
Percentage of buffy coat in the blood
1%
Percentage of red blood cells in the blood
45%
Plasma consist of how many percent of proteins?
7%
What are the proteins that can be found in the plasma? Write their corresponding percentages.
Fibrinogen (7%)
Albumin (55%)
Globulin (38%)
Buffy Coat contains:
WBC
Platelets
What are the layers of the Buffy Coat?
Uppermost Layer
Middle Layer
Lower Layer
What if Factor I?
Fibrinogen
Classifications of the Globulin
Alpha
Beta
Gamma
Factor V is also known as _____
Labile Factor
Factor VIII:C is also known as _____
Deficiency on Haemophilia A
Factor XIII is also known as _____
Fibrin Stabilizing Factor
Factor II is also known as _____
Prothrombin
If blood is in vitro, it coagulates _____
5-10 minutes
In vivo blood is _____
Fluid state
Blood is thick and viscous _____ thicker than water
3.5-4.5 times
Blood makes up of _____ (percentage) of the total body component or _____ (volume)
6-8%
60-80 ml/kg
Blood is approximately _____ (mass)
20 grams solid per 100 ml
Total blood volume of an adult male
5-6 liters
Total blood volume of an adult female
4-5 liter
Total blood volume of a newborn
250-350 ml
Described as the thickness and stickiness of blood
Blood viscosity
A measure of the resistance of blood to flow
Viscosity
Viscosity depends on:
Red Blood Cells
Plasma Proteins
A measure of the acidity or basicity of an aqueous solution
pH
It is the negative decimal logarithm of hydrogen concentration
pH
Normal range of pH level
7.35-7.45
Average pH level
7.40
pH of venous blood
7.35
pH of arterial blood
7.45
If the pH is less than 7.3, it is then considered _____
Acidosis
If the pH is more than 7.5, it is then considered _____
Alkalosis
pH is maintained by:
- Excretion of carbon dioxide by the lungs
- Excretion of H+ or OH by the Kidney
- By the action of buffer system
The buffer system that maintains the blood are:
Carbonate
Phosphate
Protein
Hemoglobin
It is the ratio of the density of a substance to the density of a reference substance.
Blood Specific Gravity
Specific Gravity is also called as _____
Relative Density
Specific Gravity of whole blood:
1.045-1.066
Specific Gravity of serum:
1.024-1.028
Specific Gravity of Plasma:
1.025-1.029
Specific Gravity depends on:
Red Blood Cells
Plasma Proteins
What is the color of the arterial blood?
Bright red
What is the color of the venous blood?
Dark purplish red
What is the color of the blood in pulmonary arteries and veins (Hb with O2)?
Purple
What is the color of the blood in pulmonary arteries and veins (Hb without O2)?
Blue
Concentration of solutes dissolved in the blood
Osmolality
What instrument is used to measure osmolality?
Osmometer
Reference range of osmolality in blood
281-296 milli-osmoles per kilogram (mOsms)
Functions of Blood:
- Respiratory
- Nutritional
- Excretory
- Buffering Action
- Maintenance of Constant Body Temperature
- Transportation of Hormones and Other Endocrine Secretion that Regulates Cell Function
- Body Defense Mechanism
Classification of Granulocytes:
Basophils
Eosinophils
Neutrophils
Classification of Agranulocytes
Lymphocytes
Monocytes
Aside from Proteins, give other sub classification of Plasma:
Amino Acids
Nutrients
Proteins
Nitrogenous Waste
Electrolytes
Gases