Introduction To Dermatology Flashcards

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1
Q

What are the functions of the skin?

A
Thermoregulation 
Immune system 
Barrier to harmful substances & keeps in water, electrolytes and macromolecules
Sensation
Vitamin D synthesis
Interpersonal communication (appearance)
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2
Q

What are the 5 layers of the skin?

A
Stratum corneum
Stratum lucidum 
Stratum granulosum 
Stratum spinosum 
Stratum basale
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3
Q

What cells are present within the dermis?

A

Fibroblasts
Macrophages
Dendritic cells

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4
Q

What cells are present in the epidermis?

A

Melanocytes
Keratinocytes
Langerhans cells

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5
Q

What are the different parts of the nail?

A
Hyponychium 
Nail plate 
Lateral nail fold
Lunula 
Cuticle 
Proximal nailfold 
Nail matrix.
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6
Q

What are the causes of external skin disease?

A

Photosensitivity (commonly caused by medications)
Cold injury i.e. frost bite, chilblains, cold urticaria
Trauma i.e. dermatitis artefacta

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7
Q

What are internal causes of skin disease?

A

Genetic i.e. neurofibromas
Drug reactions
Autoimmune

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8
Q

What are the names of a small and large fluid filled lesion?

A
Small = vesicle 
Large = bulla
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9
Q

What are the terms used to describe small and large circumscribed, non raised areas of the skin?

A
Small = macule
Large = patch
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10
Q

What is term describes a small and large raised area of the skin?

A
Small = papule 
Large = plaque
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11
Q

What the difference between an erosion and an ulcer?

A

An erosion is loss of the epidermis but an ulcer is loss of epidermis and dermis

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12
Q

What is the name of the skin condition which has erythematous plaques + bullae?

A

Bullous pemphigoid

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13
Q

What is the presentation of leukocytoclastic vasculitis?

A
A mix of; 
Maculae 
Petechiae 
Purpura 
Papule
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14
Q

Give examples of cutaneous signs of certain conditions.

A

Eruptive xanthoma = hyperlipidaemia
Acanthosis nigricans = insulin resistance, obesity, malignancy
Pre tibial Myxedema = Graves’ disease

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15
Q

What investigation would you carry out if you suspected a bacterial skin infection?

A

Charcoal swab

MC & S for microscopy, culture and sensitivities

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16
Q

What investigations would you carry out if you suspected a viral skin infection?

A

Viral swab for PCR
Swab vesicle / bulla if vesicular eruption
Throat swab if systemic illness

17
Q

What investigations would you carry out if you suspected a fungal skin infection?

A

Skin scrapping, Nail clipping, Hair sample - For fungal cultures

18
Q

Name a condition caused by;
A) type I hypersensitivity reaction
B) type IV hypersensitivity reaction

A
A = acute urticaria
B = allergic contact dermatitis
19
Q

what medications can cause photosensitivity to the skin?

A

bendroflumethiazide
NSAIDS
tetracyclines
sulphonylureas