INTRODUCTION OF FERTILIZATION Flashcards
What is the fertilization ?
It is the fusion of the sperm cell nucleus with the egg cell nucleus to produce a zygote .
What are the stages of the Fertilization ?
✷ CAPACITATION - activation of the sperm occurs in the uterus and oviducts and is facilitated by substance of the female genital tract.
✷ ACROSOMAL REACTION - fusion of the sperm plasma membrane and the external acrosomal membrane occur. [ The acrosome reaction is associated with the release of acrosome enzymes that facilitate fertilization.
✷ PENETRATION OF THE ZONA PELLUCIDA AROUND THE OOCYTE - Once sperm penetrate the zona pullucida , the zona reaction occurs [ This reaction makes the zone pellucida.
✷ FUSION OF PLASMA MEMBRANES OF OOCYTE AND SPERM
✷ 2ND MEIOTIC DIVISION OF OOCYTE IS COMPLETED.
✷ FORMATION OF THE MALE AND FEMALE PRONUCLEI - Chromosomal material of the sperm decondensates and enlarged.
✷ MEMBRANES OF THE PRONUCLEI BREAKDOWN -chromosomes condense and arrange themselves for mitotic cell division .