Introduction and Anatomy of Lungs, Airways and Blood Supply Flashcards
What are the four functions of the respiratory system?
- Gas exchange - oxygen added to the blood from atmosphere, carbon dioxide removed from the blood into the atmosphere.
- Acid-base balance - regulation of body pH (renal function also).
- Protection from infection - goblet cells secrete mucus, cilia
- Communication - speech is produced from air passing over the vocal cords in the larynx.
Why do we breathe and why is gas exchange so important?
It is required to produce energy.
We burn oxygen to release energy in the form of ATP, producing carbon dioxide as a waste product - this is cellular respiration. External respiration acquires this O2 from the atmosphere.
CO2 is toxic and build up in the body can lead to a coma, therefore gas exchange in the lungs is important to expel it from the body.
How does blood travel in the pulmonary artery and pulmonary vein in relation to the lungs?
Pulmonary artery - travels AWAY from the heart and TOWARD the lungs, carrying deoxygenated blood rich in CO2.
Pulmonary vein - travels AWAY from the lungs and TOWARD the heart, carrying blood rich in O2.
What side of the heart does deoxygenated blood travel through?
The right side
What is the net volume of gas exchanged in the lungs per unit of time?
250ml/min O2
200ml/min CO2
This is the same for gas exchanged at tissues.
Which components make up the upper respiratory tract?
Which components make up the lower respiratory tract?
Upper - nose, pharynx, epiglottis, larynx, mouth, oesophagus, tongue
Lower - trachea, brochi, lungs, diaphragm
What does patency refer to?
Openness
How is patency maintained in the trachea?
By the C-shaped rings of cartilage.
Describe the branching of the airways?
Trachea - bronchi (2x primary bronchus) - secondary bronchus - tertiary bronchus - bronchioles (no cartilage) - alveoli (alveolus)
How does the diameter of the airways relate to resistance?
Airway diameter decreases - resistance increases.
Airway diameter increases (smooth muscle relaxes) - resistance decreases.
Why is there more resistance in the conducting zone if these airways have greater diameter?
Because although there is a smaller diameter in the bronchioles in the respiratory zone, there is a greater overall cross-sectional surface area (size of a badminton court).
What are the two types of alveolar cells and what are there functions?
Type I - most abundant cell, involved in gas exchange.
Type II - not involved in gas exchange, they secrete a surfactant which acts like a detergent, reducing surface tension and makes breathing easier.
What is the site of gas exchange between the lungs and blood, and between blood and tissues?
What is the term given to air which cannot participate in gas exchange?
Alveoli (for lungs), capillaries (for tissues)
Anatomical dead space
What is the purpose of mucus and where is it secreted from?
Moistens air
Traps particles
Gives larger surface area for cilia to act on
Produced by goblet cells
subepithelial glands
What is ventilation?
It is the movement of air into and out of the lungs i.e. the mechanics of breathing.
It does not include gas exchange with blood.