Introduction Flashcards

1
Q

What is homeostasis?

A

The state of steady internal physical and chemical conditions maintained by living systems

Dynamic equilibrium at all levels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the features of a control system?

A

Stimulus

Receptor - detects stimuli

Afferent pathway

Control centre - determines set point

Efferent pathway

Effector - causes change

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the circadian rhythm?

A

‘Biological clock’

Regulated by neurones in suprachiasmatic nucleus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What cues regulate circadian rhythm?

A
Light
Temperature
Exercise
Eating/drinking pattern 
Social interaction
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What hormone is involved in the circadian rhythm?

A

Melatonin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Where is melatonin produced?

A

Pineal gland

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is negative feedback?

A

Response in a way to reverse direction of a change

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is postive feedback?

A

Response in a way to increase the change in the same direction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Name the endocrine glands of the body

A
Hypothalamus
Pituitary gland
Pineal gland
Thyroid 
Parathyroid glands
Thymus 
Adrenal glands
Pancreas
Ovaries
Testes
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What other organs release hormones?

A
Heart
Liver
Stomach 
Kidney
Adipose tissue
Placenta
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is autocrine communication?

A

Hormone signal acts back on the cell of origin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is paracrine communication?

A

Hormone signal carried over to adjacent cells via interstitial fluid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is endocrine communication?

A

Hormone signal released into bloodstream and carried to distant target cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is neurocrine communication?

A

Hormone originates in neurone, is released into bloodstream from axon, and is carried to distant cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are the different classes of hormones?

A

Peptide
Amine
Glycoproteins
Steroids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the solubility of peptide hormones?

A

Water soluble

17
Q

What are some examples of peptide hormones?

A

Insulin
Glucagon
Growth hormone

18
Q

What is the solubility of amine hormones?

A

Adrenal medulla - water soluble

Thyroid hormones - lipid soluble

19
Q

What are some examples of amine hormones?

A

Adrenaline/Noradrenaline
Thyroid hormones
Melatonin

20
Q

What is the solubility of glycoprotein hormones?

A

Water soluble

21
Q

What are some examples of glycoprotein hormones?

A

LH
FSH
TSH

22
Q

What is the solubility of steroid hormones?

A

Lipid soluble

23
Q

What are some examples of steroid hormones?

A

Cortisol
Aldosterone
Testosterone

24
Q

How are hormones transported?

A

Some are free in blood

  • peptides
  • adrenaline

Others bound to proteins

25
Q

What are the roles of carrier proteins?

A

Increase solubility of hormone in plasma
Increase half-life
Provide a readily accessible reserve

26
Q

What factors effect hormone levels?

A

Rate of production

Rate of delivery

Rate of degradation

27
Q

How do water soluble hormones bind to cells?

A

Bind to cell surface receptors

  • GPCR
  • Tyrosine kinase
28
Q

How do lipid soluble hormones bind to cells?

A

Diffuse across plasma membrane

Bind to intracellular receptors

  • type 1 = cytoplasmic receptors
  • type 2 = DNA receptor