Intro week-newborn

Question 1

which ones of these aren't causes of jaundice within first 12 hours of life?
		○ Rhesus haemolytic disease
		○ Physiological jaundice
		○ Hereditary spherocytosis
		○ Glucose-6-phosphate dehydrogenase deficiency
		○ Sickle Cell Disease
		○ Septicaemia
		○ Extra hepatic biliary atresia

Answer 1

Not the following

• PHYSIOLOGICAL JAUNDICE (Doesn’t happen in first 24 hours)
• SICKLE SELL (neonate blood cells are Hbf not HBs/Hbss)
• EXTRA HEPATIC BILARY ALTRESIA (happens later on)

Question 2

What are the tests for neonatal jaundice?

Answer 2

SEPTIC SCREEN 
		○ Blood cultures 
		○ Urine cultures 
		○ CSF-lumbar puncture 
GROUP AND COOMBS TEST (DCT) 
		○ Checks for presence of antibodies on red cells     showing there is immune haemolysis going on 
		○ Clumping=positive test 
FBC TO TEST HEAMOGLOBIN 
MATERNAL GROUP AND ANTIBODIES

Question 3

what is a Kasai’s Hepatoportoenterostomy

Answer 3

Treatment for extrahepatic biliary atresia

Question 4

Treatment for HIE?

Answer 4

• cool to 33/34 degrees
• slows cerebral metabolism and limits release of neurotransmitters and free radicals
• 72 hours