Intro to Virology Flashcards
What microscope is used for viruses?
Electron microscope
(True or False)
Viruses have metabolic processes
False
(True or False)
Viruses are not capable of self replication
True
Viruses are inhibited by ____ & ____ agents
Interferon
Antiviral agents
(True or False)
Antiviral agents can destroy the virus
False (only inhibit viral replication)
It is a complete viral particle
Virion
The envelope of a virus is composed of a _____?
Phospholipid bilayer
These viruses are sensitive to ether, alcohol, detergents, dry heat
Enveloped viruses
These viruses are resistant to ether, alcohol, detergents, dry heat
Naked viruses
Enveloped viruses are transmitted thru?
Direct contact
Naked viruses are transmitted thru?
Fecal-oral route
It is a protein coat that encloses the genome
Capsid
Capsid is composed of structural units called?
Capsomeres
It is involved in specific binding to receptors in host cell’s membrane to facilitate entry
Spikes
Matrix proteins are found between ____ & ____
envelope & nucleocapsid
3 DNA viruses w/ circular DNA
Papillomaviridae
Polyomaviridae
Hepadnaviridae
DNA virus w/ a single stranded DNA
Parvoviridae
It gives the orientation of the reading frame
Polarity
RNA virus with DS RNA
Reoviridae
Group of viruses with a positive sense, SS RNA
Group IV
It is also known as Adsorption
Attachment
Coreceptor of HIV CD4 in lymphocytes
CXCR4
Coreceptor of HIV CD4 in macrophages
CCR5
Receptor in Rabies virus
Acetylcholine
Penetration is either thru ____ or _____
Direct fusion
Viropexis
It is called the time where infectious viral particles cannot be recovered from the cell
Eclipse phase
DNA viruses replicate in the ____
nucleus
RNA viruses replicate in the _____
cytoplasm
Largest DNA virus
Poxvirus
Release of naked viruses is thru ____
Lysis
Release of enveloped viruses is thru ____
Budding
It is the degradation of the capsid
Uncoating
It causes morphological changes in cell organelles followed by cellular lysis
Cytopathic effects
Viral infection wherein no progeny virus particles are produced
Abortive infection
Viral genetic material remains in host without viral production
Latent infection
Low level of viral production without immune clearance
Chronic infection
Viral gene product induces unregulated cellular growth forming tumors
Viral transmission
Group of viruses composed of circular gapped, DS DNA
Group VII
Group of viruses composed of negative sense, SS RNA
Group V
