Intro to Virology Flashcards
How is one exposed to Pepper Mild Mottle Virus?
Water, Feces or urine
8% of the human genome is made up of…?
endogenous retroviral sequence
What is the protein seath that protects the genome called?
Capsid
What are the 3 types of capsids?
Helical
Icosahedral
Complex
the protein layer between the capsid and envelope of a virus is called?
Tegument or matrix protein
Baltimore Classification group I
DNA (+/-)
Baltimore Classification group II
DNA (+)
Baltimore Classification group III
RNA (+/-)
Baltimore Classification group IV
RNA (+)
Baltimore Classification group V
RNA (-)
Baltimore Classification group VI
RNA (+)
requires reverse transcription
Baltimore Classification group VII
DNA (+/-)
requires reverse transcription
Hepadnaviridae has what kind of viral genome structure?
Circular
Gapped
What are the 4 types of Viral Genome Structuce
Linear
Circular
Gapped
Segmented
Influenza has what kind of viral genome structure?
Segmented
What makes up the eclipse phase?
Adsorption
Intimate Contact
Penetration and Uncoating
What is burst?
Lytic cycle releasing the virions
How does Fusion Penetration work?
envelope fuses with cell membrane then ejects virus into the cell cytoplasm
How does Viropexis work?
An envoloped virus creates a capsule for it self (reverse budding) and then enters the cytoplasm via fusion with the capsule.
How do encapsulated viruses (no envelope) enter the cytoplasm?
via clathrin-mediated endocytosis (Most common method)
What is susceptibility?
whether a cell expresses the proper receptors for a virus to gain entry to the cell
What is Permissivity?
If the cell contains the proper enzymes for viral replication
What do cells need to become infected?
They need to be both susceptible and permissive.
What is a retroviruse?
RNA viruses that reproduce through a DNA intermediate
