Antimicrobials I Flashcards
Beta-Lactamase inhibitors (3)
Clavulanic acid
Sulbactam
Tazobactam
Carbapenems (1)
Imipenem
Monobactams
Aztreonam
Other antibiotics
Bacitracin
Vancomycin
Daptomycin
there are 5 generations of?
Caphalosporins
1st gen (2)
Cefazolin
Cephalexin
2nd gen (3)
Cefaclor
Cefuroxime
Cefoxitin
3rd gen (4)
Cefdinir
Cefotaxime
Ceftazidime
Ceftriaxone
4th gen (1)
Cefepime
5th gen (1)
Ceftavoline
Beta Lactams are inactive against?
Organisims w/o peptidoglycans
Beta-lactams must do what to be effective?
transpeptidase enzymes
What drugs are Very susceptible to Beta- Lactamases? and work well against gram pos.
Natural Penicillins
What drugs target staph aureus? (4)
Methiciliin, nafcillin, oxacillin, and dicloxacicillin
Aminopencillins target what kind of microb?
Gram neg.
Ampicillin, amoxicillin
What drug is the first-line of treatment for staph endocarditis
Nafcillin
Which drug is the broadest spectrum of the antipseudomonal penicillins?
Piperacillin
What may happen with a large dose of Pen G?
Nervous system issues
If a patient has a history of anaphylaxis they cannot take what?
Cephalosporins
What do the 1st gen of cephalosporins not penetrate?
the CNS
1st gen is not what?
the drug of choice for any infection
Which drug has the largest spectrum available to man?
Imipenem