Antimicrobials I Flashcards

1
Q

Beta-Lactamase inhibitors (3)

A

Clavulanic acid
Sulbactam
Tazobactam

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2
Q

Carbapenems (1)

A

Imipenem

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3
Q

Monobactams

A

Aztreonam

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4
Q

Other antibiotics

A

Bacitracin
Vancomycin
Daptomycin

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5
Q

there are 5 generations of?

A

Caphalosporins

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6
Q

1st gen (2)

A

Cefazolin

Cephalexin

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7
Q

2nd gen (3)

A

Cefaclor
Cefuroxime
Cefoxitin

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8
Q

3rd gen (4)

A

Cefdinir
Cefotaxime
Ceftazidime
Ceftriaxone

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9
Q

4th gen (1)

A

Cefepime

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10
Q

5th gen (1)

A

Ceftavoline

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11
Q

Beta Lactams are inactive against?

A

Organisims w/o peptidoglycans

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12
Q

Beta-lactams must do what to be effective?

A

transpeptidase enzymes

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13
Q

What drugs are Very susceptible to Beta- Lactamases? and work well against gram pos.

A

Natural Penicillins

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14
Q

What drugs target staph aureus? (4)

A

Methiciliin, nafcillin, oxacillin, and dicloxacicillin

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15
Q

Aminopencillins target what kind of microb?

A

Gram neg.

Ampicillin, amoxicillin

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16
Q

What drug is the first-line of treatment for staph endocarditis

A

Nafcillin

17
Q

Which drug is the broadest spectrum of the antipseudomonal penicillins?

A

Piperacillin

18
Q

What may happen with a large dose of Pen G?

A

Nervous system issues

19
Q

If a patient has a history of anaphylaxis they cannot take what?

A

Cephalosporins

20
Q

What do the 1st gen of cephalosporins not penetrate?

A

the CNS

21
Q

1st gen is not what?

A

the drug of choice for any infection

22
Q

Which drug has the largest spectrum available to man?

A

Imipenem