Intro to Virology Flashcards

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1
Q

protein shell, or coat, that encloses the nucleic acid

genome

A

Capsid

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2
Q

morphologic units seen in the electron microscope on
the surface of icosahedral virus particles; represent
clusters of polypeptides

A

Capsomeres

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3
Q

a virus particle that is functionally deficient in some

aspects of replication

A

Defective virus

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4
Q

lipid-containing membrane that surrounds some virus
particles; acquired during viral maturation by a
budding process through a cellular membrane

A

Envelope

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5
Q

virus-encoded glycoproteins or projections exposed

on the surface of the envelope

A

Peplomers

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6
Q

the protein-nucleic acid complex representing the

packaged form of the viral genome

A

Nucleocapsid

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7
Q

the basic protein building block of the coat; also

known as protomer

A

Structural units

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8
Q

single folded viral polypeptide chain

A

Subunit

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9
Q

the complete virus particle; serve to transfer the viral

nucleic acid from one cell to another

A

Virion

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10
Q

very small viruses with a particle size of about 18-

26 nm

A

Parvoviruses

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11
Q

example of parvoviruses

A

HPV B19

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12
Q

most well-known among
polyomaviruses; causes progressive multifocal
leukoencephalopathy

A

JC virus

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13
Q

wart” viruses which can cause genital cancer

A

Papillomaviruses

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14
Q

some types can persist in lymphoid tissue
• some cause acute respiratory disease,
conjunctivitis, and gastroenteritis

A

adenoviruses

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15
Q

cause acute and chronic hepatitis

A

hepadnaviruses

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16
Q

oral and genital

lesions

A

HSV 1 & 2

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17
Q

infectious mononucleosis

and assoc with human neoplasms

A

Epstein-Barr virus

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18
Q

Assoc. with Kaposi

sarcoma

A

Human herpesvirus 8

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19
Q

tend to produce vesicular skin

lesions

A

poxviruses

20
Q

example of poxviruses

A

smallpox, vaccinia,

molluscum contagiosum

21
Q

Include the torque teno viruses

A

Anelloviruses

22
Q

picornaviruses that infect humans

A

entero
rhino
hapato

23
Q

causes hepatatis A

A

Hepatovirus

24
Q

Associated with gastroenteritis in humans and

animals

A

astroviruses

25
Q

Similar size to picornaviruses but particles display

a distinctive star-shaped outline on their surfaces

A

Astroviruses

26
Q

cause of epidemic acute

gastroenteritis

A

Norwalkvirus

27
Q

Cup-shaped depression on the surfaces of the

particles

A

Caliciviruses

28
Q

Human Hepatitis E virus
Small prticles (27-34 nm), ether resistant, ssRNA,
lacks genome-linked protein (VPg)
Similar to calicivirus

A

Hepeviruses

29
Q

Reovirus that cause gastroenteritis and has a distinct wheel shaped appearance

A

Rotavirus

30
Q

(Colorado tick fever virus)

A

Coltivirus

31
Q

examples of Togaviruses

A

Alphavirus, Rubella virus (no arthropod

vector), Eastern equine encephalitis virus

32
Q

Mature virions of these virus accumulate within the cisternae of
the ER

A

Flaviviruses

33
Q

Yellow fever virus, Dengue virus, Zika

virus, Hepatitis C virus is included

A

Flaviviruses

34
Q

virions incorporate host cell ribosomes during
maturation, giving the particles “sandy”
appearance

A

Arenaviruses

35
Q

Example:Lassa fever

A

Arenaviruses

36
Q

Have petal-shaped projections arranged in a fringe

A

Coronaviruses

37
Q

MERS COV and SARS are an example of this virus

A

Coronaviruses

38
Q

Round or filamentous particles with surface
projections that contains hemagglutinin or
neuraminidase activity

A

Orthomyxoviruses

39
Q

Envelope is acquired by budding in the Golg

A

Bunyaviruses

40
Q

Cause hemorrhagic fevers and neuropathy as

well as severe pulmonary syndrome

A

Hantaviruses

41
Q

Transmitted by persistently infected rodents
(not by arthropods) via aerosols of
contaminated excreta

A

Hantaviruses

42
Q

Unique among nonsegmented, negative sense

RNA viruses

A

Bornaviruses

43
Q

Resembling a bullet, flat at one end and round at

the other

A

Rhabdoviruses

44
Q

Cause acquired-immunodeficiency syndrome

AIDS

A

Retroviruses

45
Q

Similar to orthomyxovirus but larger

A

Paramyxoviruses

46
Q

Example: Mumps, measles, parainfluenza,
metapneumo, and respiratory syncytial virus
(RSV)

A

Paramyxoviruses

47
Q

Examples:Marburg and Ebola viruses

A

Filoviruses