Intro to Virology Flashcards
protein shell, or coat, that encloses the nucleic acid
genome
Capsid
morphologic units seen in the electron microscope on
the surface of icosahedral virus particles; represent
clusters of polypeptides
Capsomeres
a virus particle that is functionally deficient in some
aspects of replication
Defective virus
lipid-containing membrane that surrounds some virus
particles; acquired during viral maturation by a
budding process through a cellular membrane
Envelope
virus-encoded glycoproteins or projections exposed
on the surface of the envelope
Peplomers
the protein-nucleic acid complex representing the
packaged form of the viral genome
Nucleocapsid
the basic protein building block of the coat; also
known as protomer
Structural units
single folded viral polypeptide chain
Subunit
the complete virus particle; serve to transfer the viral
nucleic acid from one cell to another
Virion
very small viruses with a particle size of about 18-
26 nm
Parvoviruses
example of parvoviruses
HPV B19
most well-known among
polyomaviruses; causes progressive multifocal
leukoencephalopathy
JC virus
wart” viruses which can cause genital cancer
Papillomaviruses
some types can persist in lymphoid tissue
• some cause acute respiratory disease,
conjunctivitis, and gastroenteritis
adenoviruses
cause acute and chronic hepatitis
hepadnaviruses
oral and genital
lesions
HSV 1 & 2
infectious mononucleosis
and assoc with human neoplasms
Epstein-Barr virus
Assoc. with Kaposi
sarcoma
Human herpesvirus 8