Intro to the Pedigree Flashcards
The _______ is the affected member through whom a family with a genetic disorder is brought to attention.
proband
Single-gene disorders (also called _____) often present with characteristic and recognizable patterns in pedigrees.
Mendelian disorders
genotype
the set of alleles that make up a genetic constitution (usually we are talking about a single locus)
The __________ is the set of alleles that make up a genetic constitution.
genotype
Single-gene disorders (also called Mendelian disorders) often present with _______.
characteristic and recognizable patterns in pedigree
Phenotype
the observable expression (of a genotype) as a morphological, clinical, cellular, or biochemical trait
_______ (also called Mendelian disorders) often present with characteristic and recognizable patterns in pedigrees.
Single gene disorders
____________ are couples who have >1 known ancestors in common.
Consanguineous matings
The __________ is the observable expression of a genotype.
phenotype
pedigree
graphical representation of the family tree
consanguineous matings
incest; Couples who have >1 known ancestors in common
A ______ is useful for identifying possible patterns of inheritance and estimating genetic risks to current and future family members
pedigree
proband
The affected member through whom a family with a genetic disorder is brought to attention
Why is a pedigree useful?
for identifying possible patterns of inheritance and estimating genetic risks to current and future family members
consultand
the person who brings the family to attention (can be affected or unaffected)
