Intro to physiology Flashcards

Semester 1 Year 1

1
Q

Where is intracellular fluid found?

A

Inside cells

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2
Q

What separates intracellular and extracellular fluid?

A

A plasma membrane

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3
Q

What is extracellular fluid separated into?

A

Blood plasma and interstitial fluid

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4
Q

Where is interstitial fluid found?

A

Surrounds cells

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5
Q

What does blood plasma regulate?

A

Oxygen, glucose, ions, volume

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6
Q

What does interstitial fluid regulate?

A

Glucose, ions

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7
Q

What does intracellular fluid regulate?

A

ATP, glucose, ions, volume

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8
Q

What does the whole body regulate?

A

Arterial blood pressure, core body temperature

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9
Q

What is homeostasis?

A

The mechanism for the maintenance of steady state of the internal environment

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10
Q

Homeostasis is a what process?

A

An active process, so requires energy

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11
Q

What is negative feedback?

A

When the change is in the opposite direction to the input

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12
Q

How does negative feedback occur?

A
  • receptors sense the input (change in environment)
  • feed into control centre (brain - hypothalamus or brain stem) which compares it to the set point (steady state)
  • if input is different to set point, creates an output signal
  • sent to effector, which produces a change
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13
Q

What is redundancy?

A

There are multiple mechanisms for many vital parameters

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14
Q

Why is redundancy important?

A

If a mechanism isn’t working, a different one can be used to correct the change

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15
Q

What is osmolality and what is its units?

A

The total concentration of all the particles that are free in a solution - mOsm (milliosmoles per kg of water)

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16
Q

Why is osmolality the same across all liquids in the body?

A

Prevent movement of water into and out of cells, so they won’t swell or shrink

17
Q

Are there more Na+ ions in the ECF or ICF?

A

More in the ECF
Less in the ICF

18
Q

Are there more K+ in the ECF or ICF?

A

More in the ICF
Less in the ECF

19
Q

Are there more Cl- in the ECF or ICF?

A

More in the ECF
Less in the ICF

20
Q

Are there more Ca2+ in the ECF or ICF?

A

More in the ECF
Less in the ICF

21
Q

Overall, does the ECF or ICF have a greater ion concentration?

A

ECF

22
Q

What is the phospholipid bilayer made up of?

A

Phospholipids: phosphate head, lipid tail. Other lipid components e.g cholesterol

23
Q

Describe the structure of a phospholipid

A

Phosphate head:
Hydrophilic, polar, interacts with water
Lipid tail:
Hydrophobic, non-polar, interacts poorly with water

24
Q

What are phospholipid bilayers permeable to?

A

Hydrophobic molecules e.g steroid hormones

25
Q

What are phospholipid bilayers partially permeable to?

A

Uncharged, polar molecules

26
Q

What are phospholipid bilayers impermeable to?

A

Large molecules + charged, water soluble substances (ions)

27
Q

What is the purpose of membrane proteins?

A
  • provide channels through membrane
  • allows polar molecules to pass through membrane