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Biochemistry - 1 > Intro To Hormones > Flashcards

Intro To Hormones Flashcards

1
Q

Estrogen:

Chemical composition
Solubility
Receptor
Mediator

A

Steroid
Lipophilic
Intracellular
HRC/HRE

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2
Q

Aldosterone:

Chemical composition
Solubility
Receptor
Mediator

A

Steroid
Lipophilic
Intracellular
HRE/HRE

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3
Q

Insulin

Chemical composition
Solubility
Receptor
Mediator

A

Polypeptide
Hydrophilic
Cell surface
2nd msg

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4
Q

Ghrelin

Chemical composition
Solubility
Receptor
Mediator

A

Polypeptide
Hydrophilic
Cell surface
2nd msg

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5
Q

T3 & T4

Chemical composition
Solubility
Receptor
Mediator

A

Amino acid
Lipophilic
Intracellular
HRC/HRE

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6
Q

Identify if Lipophilic/hydrophilic:

TSH

A

Hydrophilic

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7
Q

Identify if Lipophilic/hydrophilic:

Testosterone

A

Lipophilic

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8
Q

Identify if Lipophilic/hydrophilic:

Progesterone

A

Lipophilic

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9
Q

Identify if Lipophilic/hydrophilic:

Growth hormone

A

Hydrophilic

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10
Q

Identify if Lipophilic/hydrophilic:

Oxytocin

A

Hydrophilic

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11
Q

Identify if Lipophilic/hydrophilic:

Somatostatin

A

Hydrophilic polypeptide

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12
Q

Identify if Lipophilic/hydrophilic:

Retinoic acid

A

Lipophilic

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13
Q

Identify if Lipophilic/hydrophilic:

Cortisol

A

Lipophilic

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14
Q

Identify if Lipophilic/hydrophilic:

Progestin

A

Lipophilic

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15
Q

Identify if Lipophilic/hydrophilic:

LH

A

Hydrophilic

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16
Q

Identify if Lipophilic/hydrophilic:

Glucagon

A

Hydrophilic - adenylyl cylase

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17
Q

Identify if Lipophilic/hydrophilic:

ACTH

A

Hydrophilic polypeptide

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18
Q

Ligand and Receptor should be specific for each other. T/F

A

T

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19
Q

Type of cell signal that Transmit signal in a short distance

A

Paracrine

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20
Q

Type of cell signal that Transmit signal in a long distance

A

Endocrine

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21
Q

Type of cell signal that Transmit signal to itself

A

Autocrine

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22
Q

Type of cell signal that Transmit signal via direct contact with another cell receptor

A

Juxtacrine

23
Q

Example of paracrine

A

Synaptic signaling

24
Q

Cell signaling that needs circulatory system to transport hormones

A

Endocrine

25
Q

Serves as binding and effector site

A

Receptors

26
Q

Conversion from intercellular to intracellular

A

Signal transduction

27
Q

2ndary messanger that Stimulates calcium

A

IP3

28
Q

2ndary messenger that stimulates PKA

A

DAG

29
Q

How to terminate cell signaling?

A

Degradation of receptor
Degradation of 2nd messengers
GTP to GDP
Deactivation using kinases/phophatase

30
Q

Which of the following statements regarding termination of cell signaling true?

A. Activation of the 1st msg
B. Conversion of GDP to GTP
C. Dehydration of receptor
D. Stimulation of kinase by phosphatasw

A

C

31
Q

Transport system used by most sugars

A

Facilitated diffusion

32
Q

Transport system that uses energy and move against concentration gradient

A

Active transport

33
Q

Transport system that move 02, c02, lipid soluble sunstances

A

Simple diffusion

34
Q

Transport channel that open and closes

A

Gated ion channels

35
Q

Chemical composition of hormones

A

Amino acid
Polypeptide
Steroids

36
Q

Group I hormone class:

Solubility

A

Lipophilic

37
Q

Group I hormone class:

Half life

A

Long

38
Q

Group I hormone class:

Receptor

A

Intracellular

39
Q

Group I hormone class:

Contains transport proteins

A

Yes

40
Q

Group II hormone class:

Contains transport proteins

A

No

41
Q

Group II hormone class:

Half life

A

Short

42
Q

Group II hormone class:

Mediators

A

2nd messengers (IP3, cAMP, metabolites of phosphoinositol

43
Q

Group II hormone class:

Solubility

A

Hydrophilic

44
Q

Group II hormone class:

Solubility

A

Hydrophilic

45
Q

Phosphorylates SH2 domain

A

Tyrosine kinase

46
Q

Activates SMAD proteins

A

Serine/threonine receptor kinase

47
Q

Activates signal transduction receptor

A

JAK-STAT receptor

48
Q

What is the correct order sequence of events of the growth hormone signal transduction process?

A 
Binding of receptor
Dimerization
Auto cross phosphorylation
Activation of Ras
Complex assembly
49
Q

TSH

Hydrophilic or lipophilic amino acid?

A

Hydropholic

50
Q

Are all amino acid lipophilic

A

No

51
Q

Intercellular ; signaling between cells

Intracellular ; ________________

A

Signal that triggers a response within the cell

52
Q

Signal that triggers a response within the cell

A

Intracellular

53
Q

Signal between cells

A

Intercellular

54
Q

Chemical messengers of the immune system

A

Cytokines

Biochemistry - 1 (6 decks)

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