Intro To Hormones Flashcards by PATRICIA PAULINE PERALTA

Q

Estrogen:

Chemical composition
Solubility
Receptor
Mediator

A

Steroid
Lipophilic
Intracellular
HRC/HRE

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Q

Aldosterone:

Chemical composition
Solubility
Receptor
Mediator

A

Steroid
Lipophilic
Intracellular
HRE/HRE

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Q

Insulin

Chemical composition
Solubility
Receptor
Mediator

A

Polypeptide
Hydrophilic
Cell surface
2nd msg

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Q

Ghrelin

Chemical composition
Solubility
Receptor
Mediator

A

Polypeptide
Hydrophilic
Cell surface
2nd msg

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Q

T3 & T4

Chemical composition
Solubility
Receptor
Mediator

A

Amino acid
Lipophilic
Intracellular
HRC/HRE

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Q

Identify if Lipophilic/hydrophilic:

TSH

A

Hydrophilic

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Q

Identify if Lipophilic/hydrophilic:

Testosterone

A

Lipophilic

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Q

Identify if Lipophilic/hydrophilic:

Progesterone

A

Lipophilic

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Q

Identify if Lipophilic/hydrophilic:

Growth hormone

A

Hydrophilic

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Q

Identify if Lipophilic/hydrophilic:

Oxytocin

A

Hydrophilic

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Q

Identify if Lipophilic/hydrophilic:

Somatostatin

A

Hydrophilic polypeptide

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Q

Identify if Lipophilic/hydrophilic:

Retinoic acid

A

Lipophilic

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Q

Identify if Lipophilic/hydrophilic:

Cortisol

A

Lipophilic

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Q

Identify if Lipophilic/hydrophilic:

Progestin

A

Lipophilic

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Q

Identify if Lipophilic/hydrophilic:

LH

A

Hydrophilic

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Q

Identify if Lipophilic/hydrophilic:

Glucagon

A

Hydrophilic - adenylyl cylase

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Q

Identify if Lipophilic/hydrophilic:

ACTH

A

Hydrophilic polypeptide

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Q

Ligand and Receptor should be specific for each other. T/F

A

T

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Q

Type of cell signal that Transmit signal in a short distance

A

Paracrine

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Q

Type of cell signal that Transmit signal in a long distance

A

Endocrine

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Q

Type of cell signal that Transmit signal to itself

A

Autocrine

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Q

Type of cell signal that Transmit signal via direct contact with another cell receptor

A

Juxtacrine

Q

Example of paracrine

A

Synaptic signaling

Q

Cell signaling that needs circulatory system to transport hormones

A

Endocrine

Serves as binding and effector site

Receptors

Conversion from intercellular to intracellular

Signal transduction

2ndary messanger that Stimulates calcium

IP3

2ndary messenger that stimulates PKA

DAG

How to terminate cell signaling?

Degradation of receptor Degradation of 2nd messengers GTP to GDP Deactivation using kinases/phophatase

Which of the following statements regarding termination of cell signaling true? A. Activation of the 1st msg B. Conversion of GDP to GTP C. Dehydration of receptor D. Stimulation of kinase by phosphatasw

C

Transport system used by most sugars

Facilitated diffusion

Transport system that uses energy and move against concentration gradient

Active transport

Transport system that move 02, c02, lipid soluble sunstances

Simple diffusion

Transport channel that open and closes

Gated ion channels

Chemical composition of hormones

Amino acid Polypeptide Steroids

Group I hormone class: Solubility

Lipophilic

Group I hormone class: Half life

Long

Group I hormone class: Receptor

Intracellular

Group I hormone class: Contains transport proteins

Yes

Group II hormone class: Contains transport proteins

No

Group II hormone class: Half life

Short

Group II hormone class: Mediators

2nd messengers (IP3, cAMP, metabolites of phosphoinositol

Group II hormone class: Solubility

Hydrophilic

Group II hormone class: Solubility

Hydrophilic

Phosphorylates SH2 domain

Tyrosine kinase

Activates SMAD proteins

Serine/threonine receptor kinase

Activates signal transduction receptor

JAK-STAT receptor

What is the correct order sequence of events of the growth hormone signal transduction process?

``` Binding of receptor Dimerization Auto cross phosphorylation Activation of Ras Complex assembly ```

TSH Hydrophilic or lipophilic amino acid?

Hydropholic

Are all amino acid lipophilic

No

Intercellular ; signaling between cells | Intracellular ; ________________

Signal that triggers a response within the cell

Signal that triggers a response within the cell

Intracellular

Signal between cells

Intercellular

Chemical messengers of the immune system

Cytokines