INTRO TO HEMATOLOGY Flashcards
Explain what Hematology is.
It is the study of different blood cells that is present in the body.
To record the phenotypes, genotypes and appearance of different blood cells. What are we going to use?
Staining
Counting
Analyzing
Since we are able to record the phenotypes, genotypes and appearance of the different blood cells through staining, counting and analyzing. Therefore, we can accurately __________, ____________, and __________ any disease related to these cells.
Predict, Detect, and Diagnose
What test is routinely ordered by all physicians before testing is conducted?
Complete Blood Count
What type of fluid is blood?
Nutritive fluid
What are the 4 main functions of blood?
- Transport
- Buffer system
- Regulation (Maintenance of constant body temperature)
- Defense
What does the blood transports?
A. Gases
B. Enzymes
C. Waste products
D. Hormones
What function of blood describes this: “Blood assists in the PRESERVATION of almost neutral reaction in the tissues”.
Buffer system
The blood is the buffer system of the body. Therefore, what does it maintain?
Normal water balance
Fluid distribution
What is normal pH value of the blood?
5.8
One of the function of blood is regulation. Therefore, circulating blood _______________ variation in ________________.
Minimizes; Local temperaure
The blood contains the cellular structures in the blood that help destroy foreign bodies. What are these?
Proteolytic enzymes
Antibodies
What does “phago” or “phage” mean?
To eat
What WBC is in charge of engulfing foreign bodies?
Macrophage
This is referred to as the biggest cell.
Macrophage
What is the linear development of Macrophage?
Monocytes
These WBC are also called ___________because these WBC have a hand in presenting the foreign substance to the T-cells and B-cells.
Antigens presenting cell
What WBC will first respond to the site of infection?
Neutrophils
This WBC will first respond to the site of infection since they are the most abundant in the Blood. However they stay there the shortest time. What is this WBC?
Neutrophils
For how long does the Neutrophils stay at the site of infection?
6 - 10 hours
What WBC is the most abundant in the BODY?
Lymphocytes
For whole blood, what is its color?
Red
How viscous is blood compared to water?
3 -5x
In what state does the blood circulates?
Liquid
How long does it take for the blood to coagulate upon removal from the body?
5 - 10 minutes
If the body’s pH is 5.8. How about the blood?
7.35 - 7.45
What is the specific gravity of the whole blood?
1.048 - 1.086
What is the specific gravity of the serum?
1.026 - 1.031
What is the specific gravity of the RBC?
1.092 - 1.095
What is the volume of blood in our body?
5 -6 liters (7-8%)
For males how many mL of blood per kg body weight?
76mL
For FEMALES, how many mL per kg body weight?
68mL
In the composition of blood, what contains the 45%?
RBC + Polymorphonuclear cells
- Eosinophil
- Neutrophil
In the composition of blood, what does the 1% contains?
Platelets + peripheral blood mononuclear cells (PBMCs)
- Lymphocytes
- MOnocytes
In the composition of blood, what does the 55% contains?
Plasma
- Water
-Proteins
- Electrolytes
In the composition of blood which part has the clotting factors?
The 45%
When referring to plasma, it is called a “whole blood”. Why?
Because it still contains clotting factors which are protein.
What PROTEIN in present in the body and is the MOST COMMON CARRIER?
Albumin
What PROTEIN in present in the body and is the MOST COMMON CARRIER?
Albumin
This is a form of protein that migrates similarly to Hemoglobin.
Albumin
The protein structure of Hemoglobin is Quaternary. Therefore, how many heme and globin does it contain?
4 globin and 1 Heme
What can be found in the Hemoglobin?
Globin
What happens if too much Albumin is excreted from the intercellular fluid?
It leads to Edema
What do you call the liquid portion of the anticoagulated blood?
Plasma
What do you call the liquid portion of the coagulated blood?
Serum
What happens if the blood becomes too acidic?
It induces an immune response
What term is used to “blood managing swelling”?
Normal fluid balance
This talks about the origin of the cell and how the cell will stop.
Hematopoiesis
What is the lifespan of RBC? It reproduces every?
120 days; 3 months
Thrombocytes came from the word “thrombus” which means?
To clot