Intro to Biochem

Question 1

What are the aims of biochemisty?

Answer 1

to describe and explain, in molecular terms, all chemical processes of living cells
• Structure-function
• Metabolic Regulation
• How life began?

Question 2

Who: Discovery of the role of enzymes as catalysts

Answer 2

1903
Carl Neuberg (German)

Question 3

Who: Identification of nucleic acids as information

Answer 3

1903
Carl Neuberg (German)

Question 4

Each types of biomolecules are polymers that are assembled from single units called?

Answer 4

Monomers

Question 5

-Discovered Citric Acid Cycle
-Won Nobel Prize in Physiology
or Medicine in 1953

Answer 5

1937

Sir Hans Adolf Krebs (German)

Question 6

-Discovered DNA as double helix
-Won Nobel Prize in Physiology
or Medicine in 1962

Answer 6

1953
James Watson and Francis Crick
(English)

Question 7

-Determined Insulin sequence and
structure of proteins
-Won Nobel Prize in Physiology
or Medicine in 1956

Answer 7

1955
Frederick Sanger (British)

Question 8

-Determined sequence of DNA
-Won Nobel Prize in Chemistry
in 1980

Answer 8

1980
Frederick Sanger (British)  and 
Walter Gilbert  (American)

Question 9

-Invention of PCR method
-Won Nobel Prize in Chemistry
in 1993

Answer 9

1993
Kary Mullis (American)

Question 10

MACROMOLECULE  - MONOMER?
CARBOHYDRATES	
LIPIDS	
PROTEINS  
NUCLEIC ACIDS

Answer 10

Monomer:
Monosaccharide
Not always polymers;  Hydrocarbon chains
Amino acids
Nucleotides

Question 11

MONOMER, WHAT IS ITS MACROMOLECULE?

* Simple Sugar
* Amino Acid
* Nucleotide
* Fatty Acid

Answer 11

MACROMOLECULE

* Polysaccharide
* Protein (peptide)
* RNA or DNA
* Lipid

Question 12

How do monomers form polymers?

Answer 12

In condensation reactions (dehydration synthesis), a molecule of water is removed from two monomers as they are connected together.

Question 13

What aim of biochemistry deals with physiological mechanism by which the body takes in nutrients and delivers required energy?

Answer 13

metabolic regulation