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RENAL II Exam 3 > Intro to Antihypertensive Agents V > Flashcards

Intro to Antihypertensive Agents V Flashcards

1
Q

acebutolol

A

beta-blocker

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2
Q

atenolol

A

beta-blocker

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3
Q

betaxolol

A

beta-blocker

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4
Q

bisoprolol

A

beta-blocker

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5
Q

carteolol

A

beta-blocker

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6
Q

carvedilol

A

beta-blocker

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7
Q

esmolol

A

beta-blocker

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8
Q

labetolol

A

beta-blocker

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9
Q

metoprolol

A

beta-blocker

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10
Q

nadolol

A

beta-blocker

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11
Q

nebivolol

A

beta-blocker

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12
Q

penbutolol

A

beta-blocker

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13
Q

pindolol

A

beta-blocker

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14
Q

propranolol

A

beta-blocker

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15
Q

timolol

A

beta-blocker

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16
Q

doxazosin

A

alpha1 blocker

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17
Q

prazosin

A

alph1 blocker

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18
Q

terazosin

A

alpha1 blocker

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19
Q

clonidine

A

central acting sympatholytic

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20
Q

guanabenz

A

central acting sympatholytic

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21
Q

guanfacine

A

central acting sympatholytic

22
Q

methyldopa

A

central acting sympatholytic

23
Q

alpha1

A

vasculature

24
Q

beta1

25
Q

catecholamine

A

from adrenal medulla

-affect tone of resistance in vessels as well as HR and output

26
Q

beta1 selective blocker

A

metoprolol and atenolol

27
Q

non-selective beta blocker

A

propanolol

28
Q

ISA

A

intrinsic sympathomimmetic activity

  • low sympathetic tone - agonist
  • high sympathetic tone - antagonist
29
Q

carvedilol and labetalol

A

alpha and beta blockers

30
Q

nadolol

A

non-selective beta blocker

-contraindicated in asthma

31
Q

beta2 bronchodilation

A

non-selective beta blockers

-relative contraindication

32
Q

diabetes

A

don’t want non-selective beta blocker

33
Q

beta-blockers

A

no longer first line treatment for HTN

-except when with heart failure, recent MI, or reduced left ventr. function

34
Q

labetalol

A

selective alpha 1 blocker
non-selective beta 1 and 2 blocker

partial agoninst at beta 2

  • IV for severe HTN
  • acceptable for HTN during pregnancy
35
Q

carvedilol

A

non-selective beta-blocker and alpha-1 blocker

also antioxidant

36
Q

nebivolol

A

beta1 selective blocker

  • also decreases TPR and BP
  • via increased nitric oxide formation
37
Q

phenylephrine

A

alpha agonist

alpha 1 > alpha 2

38
Q

beta blockers with vasodilator activity

A

non-selective - carteolol, carvedilol, labetalol

beta-1 selective - betaxolol, nebivolol

ex/ nebivolol - increases NO

39
Q

esmolol

A

beta1 selective
-very rapid onset and short duration of action

IV for peri-op tachycardia and HTN, hypertensive emergencies, arrhythmias

also used in electroconvulsive therapy

aka brevibloc

40
Q

prazosin

A

alpha-1 selective blocker
-no loss of alpha2 inhibition on NE release

admin of phenylephrine - no effect

41
Q

phentolamine

A

non-selective alpha blocker

  • decreased alpha 2 inhibitor
  • therefore larger increase of NE release
42
Q

men with HTN and BPH

A

alpha-1 selective blocker

-prazosin

43
Q

clonidine receptor agonist

44
Q

clonidine

A

alpha 2 receptor agonist
-central acting

increased BP, then decreased BP**

sudden withdrawal - hypertensive crisis

45
Q

dangerous effect on fetus

A

ACE (-)

-ends in pril

46
Q

methyldopa

A

converted to methyl-NE
-stored in NE vesicles

central alpha2 agonist

  • decreased sympathetic outflow
  • decreased BP

-treat HTN in pregnancy***

aka aldomet

47
Q

hypertensive emergency

A

involves organ damage

drugs given IV

48
Q

renoprotective

A

ACE (-) or ARBs

49
Q

no used unless specific indication

A

beta-blockers

50
Q

african descent

A

ARB and ACE (-) worse

RENAL II Exam 3 (17 decks)

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