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Pharm 1 > Intro > Flashcards

Intro Flashcards

1
Q

Minoxidil pharmacodynamics

A

Agents that act on ion channels

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2
Q

Insulin

A

Agents that act on cell membrane receptors

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3
Q

Heparin pharmacodynamics

A

Act on specific enzymes

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3
Q

Omeprazole pharmacodynamics

A

Agents that act on transport systems

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4
Q

Methotrexate pharmacodynamics

A

Act on specific enzymes

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5
Q

Nifedipine pharmacodynamics

A

Agents that act on ion channels

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6
Q

Cimetidine pharmacodynamics

A

Agents that act on cell membrane receptors

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8
Q

Cocaine pharmacodynamics

A

Acts on transport systems

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8
Q

Potency

A

Effect of drug relative to dose

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10
Q

Infliximab pharmacodynamics

A

Act on specific enzymes

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11
Q

Three agents that work on intracellular receptors

A

Steroids Glucocorticoids Cortisol

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11
Q

TI definition and equation

A

TI is a measure of clinical safety of a drug

TI=TD50/ED50

TD50=Dose at which toxicity occurs in 50% of cases

ED50=Dose at which half of maximum effect is reached

The closer the ED50 to the TD50 the less safe the drug is

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12
Q

Nitroglycerin pharmacodynamics

A

Act on specific enzymes

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13
Q

Three ā€œSā€s of a receptor

A

Sensitive

Selective

Specific in its response

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14
Q

Aspirin pharmacodynamics

A

Act on specific enzymes

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14
Q

Imitinib pharmacodynamics

A

Act on specific enzymes

16
Q

Procaine pharmacodynamics

A

Agents that act on ion channels

16
Q

Efficacy

A

Max therapeutic effect

17
Q

How do anticancer drugs work?

A

Binds non-specifically to large molecules

19
Q

Fluoxetine pharmacodynamics

A

Acts on transport systems

20
Q

Prazosin pharmacodynamics

A

Agents that act on cell membrane receptors

22
Q

Propranolol pharmacodynamics

A

Agents that act on cell membrane receptors

23
Q

Morphine pharmacodynamics

A

Agents that act on cell membrane receptors

24
Q

How does ethanol work?

A

Binds non-specifically to large molecules

Protein denaturance

25
Q

Tranylcypromine pharmacodynamics

A

Act on specific enzymes

Pharm 1 (8 decks)

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