Antihypertensives Flashcards
Desirable blood pressure?
115/75 or lower
Hypertensive urgency values
220/120
Secondary hypertension
We know what causes hypertension (5-10%) cocaine and oral contraceptives (increase BP) pheochromocytoma-tumor of adrenal gland
Primary hypertension
Cause is unknown
Malignant HT
220/120 or higher
Why hypertension kills
Stroke
MI
Left ventricular hypertrophy
Aneurysm
Renal failure
What controls our BP when we sit up suddenly
Neuronal-vascular control loop
What does Ca influx into vessels cause?
Contraction
What does K efflux into vessels cause?
Relaxation
Increase in cGMP in vessels causes?
Contraction
What does angiotensin II on vessels cause?
Contraction
What does DA influx into vessels cause?
Relaxation
What does endothelin receptor on vessels cause?
Contraction
When BP or Na levels in the kidney drop what happens
Renin is secreted
What controls our BP long term?
Kidney control loop (renin-angiotensin-aldosterone system)