Intravenous Medication Principles Flashcards
what drug makes intrathecal CI
vincristine
makes intrathecal fatal
types of parenteral drug administration
IV
IM
SQ
venous catheter
catheter inside of vein
for fluid and drug delivery
“line”
peripheral venous catheter
inserted into smaller veins
what vein is often used for peripheral venous catheter
cephalic vein in arm
phlebitis
vein irritation
thrombosis
clots
fluid extravasation
catheter dislodged from vein; infusion contents enter surrounding tissue
central line
empties into larger vein (superior vena cava, etc.)
used for highly concentrated drugs, long-term antibiotics, vesicants, pH/osmolality not close to blood (parenteral nutrition)
parenterally inserted central catheters (PICCs)
inserted into peripheral vein until tip ends in superior vena cava
vesicants
cause severe damage if catheter tip comes out of vein
vasopressors (dopamine, NE)
anthracyclines (doxorubicin)
vinca alkaloids (vincristine, vinblastine)
promethazine
severe tissue injury
do not give to children <2 yrs
incompatible
unsuitable to be given together
resources: Handbook on Injectable Drugs (Trissel’s); King Guide to Parenteral Admixtures; package insert
chemical incompatibility
hydrolysis, oxidation, decomposition causes degradation/toxicity
physical incompatibility
between drug and container, diluent, or another drug
