Calculations II: Compounding

Question 1

% w/v

Answer 1

g/mL

Question 2

% v/v

Answer 2

mL/100 mL

Question 3

% w/w

Answer 3

g/100 g

Question 4

ratio strength

Answer 4

one unit:total amount

convert one unit to g

Question 5

PPM

Answer 5

from percentage: move decimal L 4 spaces

to percentage: move decimal R 4 spaces

to ratio strength: equate to g substance/total mL

Question 6

specific gravity

Answer 6

weight of substance/weight of equal volume of water
g/mL

Question 7

dilution and concentration

Answer 7

Q1 x C1 = Q2 x C2

“pure” = 100%

diluent concentration = 0%

watch out for Q2 being TOTAL final weight = may need to subtract weight already started with

Question 8

osmolarity

Answer 8

always normalize to vol of 1 L (when finding weight)

mOsmol/L = wt of substance (g/L) / MW (g/mole) X valence X 1000

if you have more than 1 component (dextrose in NS + added drug) - find separate osmolarities and then add together

Question 9

dextrose dissociated particles

Answer 9

1

Question 10

mannitol dissociated particles

Answer 10

1

Question 11

potassium chloride dissociated particles

Answer 11

2

Question 12

sodium chloride dissociated particles

Answer 12

2

Question 13

magnesium sulfate dissociated particles

Answer 13

2

Question 14

calcium chloride dissociated particles

Answer 14

3

Question 15

sodium citrate dissociated particles

Answer 15

4

Question 16

finding dissociation factor/ionization i

Answer 16

1 dissociated ions = 1
2 dissociated ions = 1.8
3 dissociated ions = 2.6
4 dissociated ions = 3.4
5 dissociated ions = 4.2

Question 17

E value

Answer 17

`amt of NaCl that makes same osmolarity as drug in question

E = (58.5)(i)/(MW x 1.8)

to find NaCl equivalent of substance: weight * E

Question 18

moles and millimoles

Answer 18

mol = g/MW

mmol = mg/MW

Question 19

milliequivalents

Answer 19

mEq = (mg x valence)/MW

mEq = mmols/valence

Question 20

ammonium chloride valence

Answer 20

1

Question 21

potassium chloride valence

Answer 21

1

Question 22

potassium gluconate valence

Answer 22

1

Question 23

sodium acetate valence

Answer 23

1

Question 24

sodium bicarbonate valence

Answer 24

1

Question 25

sodium chloride valence

Answer 25

1

Question 26

calcium carbonate valence

Answer 26

2

Question 27

calcium chloride valence

Answer 27

2

Question 28

ferrous sulfate valence

Answer 28

2

Question 29

lithium carbonate valence

Answer 29

2

Question 30

magnesium sulfate valence

Answer 30

2

Question 31

KCl 10% mEq

Answer 31

20 mEq/15mL