Intravenous Anesthetics

Question 1

Is defined as the time to achieve a 50% reduction in concentration after stopping a continuous infusion.

Answer 1

Context-sensitive half-time

Question 2

Is a recognized adverse effect of etomidate.

Answer 2

Adrenocortical suppression

Question 3

Is defined as the time to achieve a 50% reduction in concentration after stopping a continuous infusion.

Answer 3

Context-sensitive half-time

Question 4

The slight delay between target blood concentration and effect organ (brain) response is known as?

Answer 4

Hysteresis

Question 5

It is the time it takes for the plasma concentration of a drug to decrease to 50% of its original concentration.

Answer 5

elimination half-time (t1/2)

Question 6

Propofol comtents (4)

Answer 6

1. 1% propofol
2. 10% soybean oil
3. 2.25% glycerol
4. 1.2% egg phospholipid

Question 7

Neuroprotection dose of propofol

Induction concentration of general anesthesia

Answer 7

8 ug/mL

3 ug/mL

Question 8

Reversal of propofol

Answer 8

Physostigmine

Question 9

Respiratory effect of propofol (maintenance dose)

Answer 9

Diminished vt

Inc RR

Question 10

In obese patients given with propofol how do you calculate its dosing?

Answer 10

LEAN BODY WEIGHT

Question 11

Anesthetic of choice for MH

Answer 11

Propofol

Question 12

Which is the ideal site to perform bier block other than the hand?

Answer 12

Antecubital vein

Question 13

Propofol infusion syndrome

Answer 13

1. Metabolic acidosis
2. HYPERkalemia
3. HYPERlipidemia
4. Rhabdomyolysis
5. Hepatomegaly
6. Renal failure
7. Arrhythmias & HF

Question 14

IV anesthetic commonly used for ECT?

Answer 14

Etomidate

Question 15

What does etomidate inhibit that causes adrenal suppression?

Answer 15

11 b hydroxylase (prevents conversion of cholesterol to cortisol)

Question 16

Other name for phencyclidine

Answer 16

Angel dust

Question 17

Which route has the highest bioavailability for ketamine?

Answer 17

IM

Question 18

How is midazolam’s effect terminated?

Answer 18

Redistribution

Question 19

2 classes of barbiturates

Answer 19

1. Oxybarbiturates

2. Thiobarbiturates

Question 20

Examples (2) of thiobarbiturates

Example of oxybarbiturates

Answer 20

1. Thiopental
2. Thiamylal
3. Methohexital

Question 21

Cardiovascular effects of barbiturates

Answer 21

1. Decrease MAP

2. Decrease cardiac output

Question 22

Barbiturates are contraindicated in patients with this disease

Answer 22

Porphyria