1 History Flashcards

1
Q

Described a mastectomy she endured after receiving a

“wine cordial” as her sole anesthetic

A

Fanny Burney

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2
Q

Summarizes the contribution of anesthesia: “BEFORE

WHOM in all time Surgery was Agony.”

A

William Thomas Green Morton

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3
Q

In the 16th century, military surgeon ________ became adept at nerve compression as a means of creating anesthesia.

A

Ambroise Paré

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4
Q

Described the technique of “refrigeration anesthesia” in which snow was placed in parallel lines across the incisional plane such that the surgical site became insensate within minutes. He also have saved numerous lives during an epidemic of diphtheria by performing tracheostomies and inserting trocars to maintain patency of the airway.

A

Marco Aurelio Severino

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5
Q

Formal manipulation of the psyche to relieve surgical pain was undertaken by 2 French physicians in the late 1820s with hypnosis, then called mesmerism.

A

Charles Dupotet and Jules Cloquet

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6
Q

In a well-attended demonstration in 1828, ______removed the breast of a 64-year-old patient while she reportedly remained in a calm, mesmeric sleep.

A

Cloquet

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7
Q

Published the book Numerous Cases of Surgical Operations Without Pain in the Mesmeric State.

A

Elliotson

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8
Q

He performed the FIRST operation using ETHER anesthesia in England and emarked, “This Yankee dodge beats mesmerism all hollow.”

A

Robert Liston

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9
Q

A Greek physician from the first century AD, commented on the analgesia of mandragora, a drug prepared from the bark and leaves of the
mandrake plant. (Soporific sponge)

A

Dioscorides

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10
Q

Prepared as indicated by published reports of the time,

the sponge generally contained _____ and _____—drugs used in modern anesthesia—in varying amounts.

A

Morphine

Scopolamine

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11
Q

This was an alcohol-based solution of opium first

compounded by Paracelsus in the 16th century.

A

Laudanum

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12
Q

In the first three decades of the 19th century, in Japan, ________ performed operations under what has been described as general anesthesia

A

Seisyu Hanaoka

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13
Q

The manuscript “On the Use of Mafutsuto,” the name given to the anesthetic method by Hanaoka, was translated into English. Written by ________, the manuscript details preanesthetic evaluation, the timing of anesthesia, and the proposed duration of surgery.

A

Hajime Matsuoka

The manuscript stated that care should be taken to ensure that lighting is appropriate; therefore it recommended that operations be performed at NOON.

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14
Q

This drug was was made by heating ammonium nitrate in the presence of iron filings.

A

Nitrous oxide

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15
Q

Nitrous oxide was first prepared in 1773 by whom?

A

Joseph Priestley

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16
Q

Priestley prepared and examined several gases, including (6)?

A
  1. Nitrous oxide
  2. Ammonia
  3. Sulfur dioxide
  4. Oxygen
  5. Carbon monoxide
  6. Carbon dioxide
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17
Q

He opened his Pneumatic Institute close to the small spa of Hotwells, in the city of Bristol, to study the beneficial effects of inhaled gases.

A

Thomas Beddoes

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18
Q

Who did he hire in 1798 to conduct research projects for the institute.

A

Humphry Davy

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19
Q

His human experimental results, combined with research on the physical properties of the gas, were published in Nitrous Oxide, a 580-page book published in 1800.

A

Humphry Davy

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20
Q

He commented that nitrous oxide transiently relieved a severe headache, obliterated a minor headache, and briefly quenched an aggravating toothache.

A

Humphry Davy

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21
Q

He commented: “As nitrous oxide in its extensive operation appears capable of destroying physical pain, it may probably be used with advantage during surgical operations in which no great effusion of blood takes place.”

A

Humphry Davy

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22
Q

Coined the term “laughing gas”

A

Humphry Davy

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23
Q

He used high concentrations of carbon dioxide in his studies on mice and dogs. He searched intentionally for an inhaled anesthetic to relieve pain in his patients.

A

Henry Hill Hickman

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24
Q

Diethyl ether may have been synthesized by 2 persons

A
  1. Arabian philosopher Jabir ibn Hayyan

2. Raymond Lully, a 13thcentury European alchemist

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25
Q

2 people who prepared diethyl ether by distilling sulfuric acid (oil of vitriol) with fortified wine to produce an oleum vitrioli dulce (sweet oil of vitriol).

A
  1. Valerius Cordus

2. Paracelsus

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26
Q

He observed that ether caused chickens to fall asleep and awaken unharmed.

A

Paracelsus

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27
Q

A medical student from Rochester, New York, may have given the first ether anesthetic in January 1842. He administered ether, from a towel, to a young woman.

A

William E. Clarke

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28
Q

William E. Clarke administered ether, from a towel, to a young woman named?

A

Hobbie

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29
Q

One of Hobbie’s teeth was then extracted without pain by a dentist named?

A

Elijah Pope

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30
Q

Two months later, on March 30, 1842, this man administered ether with a towel for surgical anesthesia in Jefferson, Georgia.

A

Crawford Williamson Long

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31
Q

Was the young man who Crawford Williamson Long administered ether through a towel, was already familiar with ether’s exhilarating effects, for he reported in a certificate that he had previously inhaled it and was fond of its use. He had two small tumors on his neck and was completed and was unaware of the removal of the tumors.

A

James M. Venable

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32
Q

In determining the first fee for anesthesia and

surgery, Long settled on a charge of?

A

2.00 USD

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33
Q

One of the first dentists to engender a
solution was? He observed a lecture-exhibition on
nitrous oxide by an itinerant “scientist,” _________, who encouraged members of the audience to inhale a sample of the gas.

A

Horace Wells

Gardner Quincy Colton

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34
Q

The following day, Colton gave Wells nitrous oxide before a fellow dentist, ________, extracted a tooth. Afterward Wells declared that he had not felt any pain and deemed the experiment a success.

A

William Riggs

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35
Q

In Boston, this man continued his interest in anesthesia and sought instruction from chemist and physician
________. After learning that ether dropped on the skin provided analgesia, he began experiments with inhaled ether, an agent that proved to be much more versatile than nitrous oxide. Bottles of liquid ether were easily
transported, and the volatility of the drug permitted effective inhalation. The concentrations required for surgical anesthesia were so low that patients did
not become hypoxic when breathing ether vaporized in air.

A

William Thomas Green Morton

Charles T. Jackson

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36
Q

After anesthetizing a pet dog, Morton became confident of his skills and anesthetized patients with ether in his dental office. Encouraged by his success, Morton sought an invitation to give a public demonstration in the Bullfinch amphitheater of the Massachusetts General Hospital (the site where Wells’ failed demonstration of the efficacy of nitrous oxide as a complete surgical anesthetic was incorrectly also thought to have occurred). Morton secured permission to provide an anesthetic to ________, a patient of surgeon John Collins Warren. Warren planned to excise a vascular lesion from the left side of his neck and was about to proceed when Morton arrived late. He had been delayed because he was obliged to wait for an instrument maker to complete a new inhaler.

A

Edward Gilbert Abbott

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37
Q

Who said, “Gentlemen, this is no humbug,” after performing a successful surgery under Morton’s anesthesia to a patient named Edward Gilbert Abbott?

A

John Collins Warren

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38
Q

Morton, wishing to capitalize on his “discovery,” refused to divulge what agent was in his inhaler. Some weeks passed before Morton admitted that the active component of the colored fluid, which he had called “______,” was simple diethyl ether.

A

Letheon

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39
Q

A debate between Morton, Wells, and Jackson, regarding the ether discovery has subsequently been termed the?

A

ETHER CONTROVERSY

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40
Q

Was a successful obstetrician in Edinburgh, Scotland,

and among the first to use ether for the relief of labor pain.

A

James Young Simpson

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41
Q

Dissatisfied with ether, Simpson soon sought a more pleasant, rapid-acting anesthetic. He and his junior associates conducted a bold search by inhaling samples of several volatile chemicals collected for Simpson by British apothecaries. ________ suggested a chemical agent _______, which had first been prepared in 1831. Simpson and his friends inhaled it after dinner at a party in Simpson’s home on the evening of November 4, 1847. They promptly fell unconscious and, when they awoke,
were delighted with their success.

A

David Waldie

Chloroform

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42
Q

Where did Simpson submitted his first publication?

A

The Lancet

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43
Q

Simpson argued against the prevailing view, which held that relieving labor pain opposed God’s will. The pain of the parturient was viewed as both a component of punishment and a means of atonement for Original Sin. Less than a year after administering the first anesthesia during childbirth, Simpson addressed these concerns in a pamphlet entitled?

A

Advanced Against the Employment of Anaesthetic Agents in Midwifery and Surgery and Obstetrics

In it, Simpson recognized the Book of Genesis as
being the root of this sentiment and noted that God promised to relieve the descendants of Adam and Eve of the curse. In addition, Simpson asserted that labor pain was a result of scientific and anatomic causes and not the result of religious condemnation.

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44
Q

Who delivered the last two children of Queen Victoria?

A

John Snow

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45
Q

What did John Snow use to deliver the children of Queen Victoria?

A

Chloroform

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46
Q

How did John Snow delivery chloroform to Queen Victoria? This technique was soon termed?

A

Handkerchief

chloroform à la reine

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47
Q

Whose work approximated the modern concept of minimum alveolar concentration?

A

John Snow
He anesthetized several species of animals with varying strengths of ether and chloroform to determine the concentration required to prevent reflex movement from sharp stimuli.

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48
Q

Snow published two remarkable books namely?

A
  1. On the Inhalation of the Vapour of Ether (1847)

2. On Chloroform and Other Anaesthetics (1858)

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49
Q

How did John Snow die and at what age?

A

Stroke

45 years old

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50
Q

Was the first Englishman to urge the now-universal practice of thrusting the patient’s jaw forward to overcome obstruction of the upper airway by the tongue.

A

Joseph Clover

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51
Q

He averted disaster by inserting a small curved cannula of his design through the cricothyroid membrane.

A

Joseph Clover

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52
Q

The first tracheal tubes were developed for the resuscitation of?

A

Drowning victims

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53
Q

The first use of elective oral intubation for an anesthetic was undertaken by Scottish surgeon?

A

William Macewan

Macewan abandoned the practice following a fatality in which a patient had been successfully intubated while awake but the tube became dislodged once the patient was asleep.

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54
Q

Designed a series of metal laryngeal tubes, which he inserted blindly between the vocal cords of children suffering a diphtheritic crisis. Three years later, He designed a second rigid tube with a conical tip that occluded the larynx so effectively that it could be used for artificial ventilation when applied with the bellows and T-piece tube designed by _____?

A

Joseph O’Dwyer

George Fell

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55
Q

The Fell–O’Dwyer apparatus, as it came to be known, was used during thoracic surgery by?

A

Rudolph Matas

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56
Q

Who said “The procedure that promises the most benefit in preventing pulmonary collapse in operations on the chest is … the rhythmical maintenance of artificial respiration by a tube in the glottis directly connected with a bellows.”

A

Rudolph Matas

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57
Q

“Die perorale Intubation,”described techniques of oral and nasal intubation that he performed with flexible metal tubes composed of coiled tubing similar to those now used for the spout of metal gasoline cans.

A

Franz Kuhn

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58
Q

What did Franz Kuhn applied to the airway for intubation?

A

Cocaine

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59
Q

Devised the first directvision laryngoscope

A

Alfred Kirstein

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60
Q

Devised a U-shaped laryngoscope by adding a handgrip that was parallel to the blade.

A

Chevalier Jackson

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61
Q

Two laryngoscopes that closely resembled modern L-shaped instruments were designed by two American surgeons?

A
  1. Henry Janeway

2. George Dorrance

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62
Q

Invented a slender, straight blade with a slight curve near the tip to ease the passage of the tube through the larynx?

A

Robert Miller

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63
Q

The Macintosh blade, which is placed in the vallecula rather than under the epiglottis, was invented as an incidental result of a?

A

Tonsillectomy

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64
Q

A technician who constructed the Macintosh blade.

A

Mr. Richard Salt

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65
Q

Who was the neophyte Magill worked with?

A

Stanley Rowbotham

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66
Q

Together, Magill and Rowbotham attended casualties
disfigured by severe facial injuries who underwent repeated restorative operations. These procedures required that the surgeon _______, have unrestricted access to the face and airway.

A

Harold Gillies

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67
Q

They developed techniques of deliberate

nasotracheal intubation. (2)

A

Ivan Magill

Stanley Rowbotham

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68
Q

Devised an aid to manipulating the catheter tip, during nasotracheal intubations.

A

Ivan Magill

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69
Q

With the war over, Magill entered civilian practice and set out to develop a wide-bore tube that would resist kinking but be conformable to the contours of the upper airway. While in a hardware store, he found mineralized red rubber tubing that he cut, beveled, and smoothed to produce tubes that clinicians around the world would come to call?

A

Magill tubes

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70
Q

He began a series of experiments that led to the

introduction of the cuffed tube.

A

Arthur Guedel

He fashioned cuffs from the rubber of dental dams, condoms, and surgical gloves that were glued onto the outer wall of tubes. Using animal tracheas donated by the family butcher as his model, he considered whether the cuff should be positioned above, below, or at the level of the vocal cords. He recommended that the cuff be positioned just below the vocal cords to seal the airway.

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71
Q

Later recommended that cuffs be constructed of two layers of soft rubber cemented together.

A

Ralph Waters

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72
Q

To encourage physicians attending a medical convention to use his tracheal techniques, he prepared the first of several “dunked dog” demonstrations. An anesthetized and intubated dog, Guedel’s own pet, “Airway,” was immersed in an aquarium.

A

Arthur Guedel

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73
Q

After a patient experienced an accidental endobronchial intubation, he reasoned that a very long cuffed tube could be used to isolate the lungs. The dependent lung could be ventilated while the upper lung was being
resected.

A

Ralph Waters

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74
Q

Arthur Guedel proposed an important modification for chest surgery, the double-cuffed single-lumen tube, which was introduced by?

A

Emery Rovenstine

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75
Q

The double-lumen tube currently most popular was designed by?

A

Frank Robertshaw

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76
Q

Robertshaw tubes were first manufactured from mineralized? But are now made of extruded plastic, a technique refined by?

A

Red rubber

David Sheridan

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77
Q

He was also the first person to embed centimeter markings along the side of tracheal tubes.

A

David Sheridan

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78
Q

lthough it was known in 1870 that a thread of glass could transmit light along the length of a bronchoscope, this man developed the first flexible fiberoptic bronchoscope.

A

Shigeto Ikeda

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79
Q

He developed the a laryngoscope, whose fiberoptic bundles lie beside a curved blade.

A

Roger Bullard (Bullard laryngoscope)

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80
Q

A Wu-scope was designed to combine and facilitate visualization and intubation of the trachea in patients with difficult airways.

A

Tzu-Lang Wu

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81
Q
First recognized the principle of the laryngeal
mask airway (LMA)
A

Dr. A. I. J. “Archie” Brain

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82
Q

Brain provided dental anesthesia via a?

A

Goldman nasal mask

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83
Q

He obtained a 4.5% concentration of chloroform in air by pumping a measured volume of air with a bellows through a warmed evaporating vessel containing
a known volume of liquid chloroform.

A

Joseph Clover

84
Q

Three American dentist-entrepreneurs developed the original series of US instruments that used compressed cylinders of nitrous oxide and oxygen.

A
  1. Samuel S. White
  2. Charles Teter
  3. Jay Heidbrink
85
Q

Before 1900, the ______ Company modified Frederick Hewitt’s apparatus and marketed its continuous-flow machine, which was refined by ____ in 1903. ______ added reducing valves in 1912.

A

S. S. White
Charles Teter
Jay Heidbrink

86
Q

Water–bubble flowmeters, introduced by _____ and ____ of Harvard University, allowed the proportion of gases and their flow rate to be approximated

A

Frederick Cotton and Walter Boothby

87
Q

During the same period in Lubeck, Germany, 2 people adapted compressed gas technology, which they had originally developed for mine rescue equipment,
to manufacture ether and chloroform–oxygen machines.

A

Heinrich Draeger and his son, Bernhaard

88
Q

Carried nitrous oxide anesthesia to its therapeutic limit by performing inductions with 100% nitrous oxide and thereafter adding small volumes of oxygen.

A

Elmer McKesson

89
Q

The oxygen flush valve is part of whose legacy?

A

Elmer McKesson

90
Q

Introduced his valveless T-piece to reduce the effort of breathing in neurosurgical patients. The T-piece soon became particularly popular for cleft palate repairs, as the surgeon had free access to the mouth.

A

Phillip Ayre

91
Q

Devised which permitted improved control of ventilation by substituting a breathing bag on the
outflow limb.

A

Gordon Jackson Rees

92
Q

2 people placed the patient’s head and neck in a box

in which positive pressure was continually maintained

A

Brauer (1904) and Murphy (1905)

93
Q

Created a negative-pressure operating chamber encompassing both the surgical team and the patient’s body and from which only the patient’s head projected.

A

Sauerbruch

94
Q

What was the first intermittent positive-pressure device called?

A

Draeger “Pulmotor

95
Q

A machine which used a piston pump to rhythmically

deliver a fixed volume of gas to the patient.

A

Morch “Respirator (Trier Morch)

96
Q

Its action was controlled by a magnetic control valve called the flasher, a type first used to provide intermittent gas flow for the lights of navigational buoys

A

Spiropulsator

97
Q

A machine used to provide ventilation for poliomyelitis victims during the Copenhagen crisis?

A

Iron lungs

98
Q

Was designed during World War II when a team of
physiologists at the University of Southern California encountered difficulties in separating inspiration from expiration in an experimental apparatus designed to provide positive-pressure breathing for aviators at high altitude.

A second valving mechanism was later designed by an aeronautical engineer?

A

Bennett valve

Forrest Bird

99
Q

The first CO2 absorber in anesthesia came in 1906 from the work of?

A

Franz Kuhn

100
Q

A few years later, the first American machine with a CO2 absorber was independently fabricated by a pharmacologist named?

A

Dennis Jackson

101
Q

He used solutions of sodium and calcium hydroxide to absorb CO2. As his laboratory was located in an area of St. Louis, Missouri, heavily laden with coal smoke, Jackson reported that the apparatus allowed him the first breaths of absolutely fresh air he had ever enjoyed in that city.

A

Dennis Jackson

102
Q

Pioneering work of Jackson in this field encouraged ___________ to introduce a simpler device using soda lime granules nine years later.

A

Ralph Waters

103
Q

Devised a freestanding machine with unidirectional valves to create a circle system and an inline CO2 absorber.

A

Brian Sword

104
Q

Further refined the CO2 absorber, increasing the efficiency of CO2 removal with a minimum of resistance for breathing.

A

James Elam

105
Q

Had been the first to apply rotameters in anesthesia for the administration of nitrous oxide and oxygen.

A

M. Neu

106
Q

Was the first temperature-compensated, accurate

vaporizer.

A

Copper Kettle

107
Q

Copper Kettle been developed by?

A

Lucien Morris

108
Q

Proposed the incorporation of a thermometer, a suggestion that was later added to all vaporizers of that class.

A

Shuh-Hsun

109
Q

2 universal vaporizers

A
  1. Copper Kettle

2. Vernitrol

110
Q

A vaporizer that featured a bimetallic strip composed of brass and a nickel–steel alloy.

A

TECOTA (TEmperature COmpensated Trichloroethylene Air)

111
Q

The first of a series of agent specific “tec” vaporizers for use in the operating room?

A

Fluotec

112
Q

He developed the habit of monitoring his patients’ pulse and one of the first clinicians to routinely perform basic hemodynamic monitoring.

A

Joseph Clover

113
Q

Urged clinicians to “strictly carry out certain simple
instructions, among which is that of never touching the pulse, in order that their attention may not be distracted from the respiration.

A

Baron Lister

114
Q

Developed a strong interest in measuring blood pressure during anesthesia.

A
  1. George W. Crile

2. Harvey Cushing

115
Q

The first precordial stethoscope was believed to have been used by?

A

Griffith Davis

116
Q

Fabricated his first esophageal stethoscope from urethral catheters and Penrose drains.

A

Albert Codesmith

117
Q

Clinical electrocardiography began with?

A

Willem Einthoven’s application of the string galvanometer

118
Q

Created an oxygen-sensing monitor worn on the pilot’s earlobe and coined the name oximeter to describe its action.

A

Glen Millikan

119
Q

Refinements of oximetry by ______, led to the

development of pulse oximetry.

A

Takuo Aoyagi

120
Q

The introduction of safety features was coordinated by?

A

American National Standards Institute (ANSI) Committee Z79

121
Q

“When a sudden need for accessory equipment arose, nurses and corpsmen were likely to respond to it by bringing parts that would not fit.”

A

Ralph Tovell

122
Q

It was used as a topical anesthetic and counterirritant; it

was so volatile that the skin transiently “froze” after it was sprayed on it.

A

Ethyl chloride

123
Q

Sprayed ethyl chloride into a patient’s mouth to “freeze” a dental abscess and caused his patient to lose consciousness

A

Carlson

124
Q

This nonflammable anesthetic found limited application in America, as it decomposed to release phosgene when warmed in the presence of soda lime.

A

Trichloroethylene

125
Q

The lightest and most reactive halogen, forms exceptionally stable bonds.

A

Fluorine

126
Q

The first commercial application of fluorine chemistry came in the form of the refrigerant?

A

Freon

127
Q

Became the first fluorinated anesthetic

A

Trifluoroethyl vinyl ether, or fluroxene

128
Q

Who created halothane?

A

Charles Suckling

129
Q

Synthesized enflurane and isoflurane?

A

Ross Terrell

130
Q

Injected aqueous opium into a dog through a goose quill attached to a pig’s bladder, rendering the animal “stupefied.”

A

Christopher Wren

131
Q

Wren similarly injected intravenous ________, an impure preparation of antimony, and observed the animals to vomit and then die.

A

crocus metallorum

132
Q

Performed the first blood transfusions of lamb’s blood into dogs and other animals.

A

Richard Lower

133
Q

Created the hollow needle for injection of morphine into nerves in the treatment of “neuralgias.”

A

Francis Rynd

134
Q

Designed the first functional syringe in 1853 for perineural injections.

A

Charles Gabriel Pravaz

135
Q

Performed what is perhaps the first successful

intravenous surgical anesthesia by injecting chloral hydrate immediately prior to incision.

A

Pierre Oré of Lyons

136
Q

Produced surgical anesthesia by intravenous injections of chloroform and ether.

A

Ludwig Burkhardt

137
Q

The first barbiturate, barbital, was synthesized by?

A

Fischer and von Mering

138
Q

The first shortacting oxybarbiturate was?

A

Hexobarbital (Evipal)

139
Q

Instructed his patients to raise one arm while he injected hexobarbital into a vein of the opposite forearm.

A

Ronald Jarman

140
Q

Synthesized thiopental (Pentothal) and thiamylal (Surital) (2)

A
  1. Donalee Tabern

2. Ernest H. Volwiler

141
Q

Ketamine was synthesized by?

A

Dr. Calvin Stevens

142
Q

The neologism “dissociative anesthesia” was created by?(2)

A
  1. Guenter Corrsen

2. Edward Domino

143
Q

Propofol was synthesised by?

A

Imperial Chemical Industries

144
Q

Synthesized nivaquine the first amino amide local

anesthetic.

A

Alfred Eihorn

145
Q

Synthesized benzocaine and procaine

A

Alfred Eihorn

146
Q

Developed lidocaine (2)

A
  1. Nils Löfgren

2. Bengt Lundquist

147
Q

Synthesized bupivacaine

A

B. Ekenstam

148
Q

The first alkaloid isolated, morphine, was extracted by?

A

Freidrich A. W. Sertürner

149
Q

Freidrich A. W. Sertürner named morphine after the Greek god of dreams?

A

Morpheus

150
Q

Codeine was isolated by?

A

Robiquet

151
Q

What was the first synthetic opioid?

A

Codeine

152
Q

Meperidine was the first synthetic opioid, was developed by? (3)

A
  1. IG Farben
  2. Otto Eisleb
  3. O. Schaumann
153
Q

What was the first parenteral NSAID indicated for postoperative pain?

A

Ketorolac

154
Q

What is analgesic potency equivalent of ketorolac to morphine?

A

6 to 8 mg

155
Q

What is the first known neuromuscular blocking agent?

A

Curare

156
Q

What was earliest clinical use of curare?

A

Treat muscle spasms of tetanus

157
Q

What drug antagonizes curare? This substance

had been isolated from the Calabar bean some 36 years earlier by Scottish pharmacologist Sir T. R. Fraser.

A

Physostigmine

158
Q

Anesthetized and intubated the trachea of a young man before injecting curare early in the course of his appendectomy.

A
Harold Griffith
Enid Johnson (resident)
159
Q

Succinylcholine was prepared by?

A

Nobel Laureate Daniel Bovet

160
Q

Developed a method for monitoring peripheral neuromuscular blockade during anesthesia (2)

A
  1. T. H. Christie

2. H. Churchill-Davidson

161
Q

Developed “train of four”

A

H. H. Ali

162
Q

This muscle relaxant was withdrawn from clinical use after several cases of intractable bronchospasm led to brain damage or death.

A

Rapacuronium

163
Q

What are the four clinical products based on the steroid parent drug d-tubocurarine?

A
  1. atracurium
  2. mivacurium
  3. doxacurium
  4. cis-atracurium
164
Q

What was the first effective local anesthetic?

A

Cocaine

165
Q

Refined the active alkaloid and named it cocaine

A

Albert Niemann

166
Q

First recognized the utility of cocaine in clinical practice.

A

Carl Koller

167
Q

The term spinal anesthesia was coined by?

A

Leonard Corning

168
Q

He offered the valuable observation that it was
most safely performed at the level of the third or fourth lumbar interspace because entry at that level was below the termination of the spinal cord.

A

Heinrich Quincke

169
Q

Discovered epinephrine, which he used to prolong the action of local anesthetics with great success.

A

Heinrich Braun

170
Q

Braun was the first person to use, which, along with

stovaine, was one of the first synthetic local anesthetics produced to reduce the toxicity of cocaine.

A

Procaine

171
Q

Discovered saddle block?

A

John Adriani

172
Q

Devised an apparatus for continuous spinal anesthesia?

A

William Lemmon

173
Q

Performed the first continuous epidural anesthetic?

A

Martinez Curbelo

174
Q

Used caudal anesthesia as a less dangerous alternative to spinal anesthesia for hernia repairs.

A

Fernand Cathelin

175
Q

Identified loss-of-resistance technique.

A

Dogliotti

176
Q

Coined the phrase regional anesthesia

A

Harvey Cushing

177
Q

Coined the term anoci-association?

A

George Crile

178
Q

Injected procaine into a vein of the upper limb between two tourniquets.

A

August Bier

“Bier block”

179
Q

Wrote the earliest textbook of local anesthesia

A

Heinrich Braun

180
Q

He formed the first American Society for Regional Anesthesia.

A

Gaston Labat

181
Q

Created the first American clinic for the treatment of chronic pain.

A

Emery A. Rovenstine

182
Q

His classic text The Management of Pain is regarded as a standard of the literature of anesthesia.

A

John J. Bonica

183
Q

Had been experimenting with several extracorporeal circuit designs and by 1947 was able to successfully
place dogs on heart–lung bypass.

A

John Gibbon

184
Q

Published one of the first articles on anesthetic management of patients undergoing surgery for coronary artery disease.

A

J. Earl Wynands

185
Q

Already known for using the V5 lead to monitor for myocardial ischemia and nitroglycerin infusions to treat ischemia, popularized the use of the PAC to detect myocardial ischemia.

A

Joel Kaplan

186
Q

Developed the first charts to record heart rate, temperature, and respiration during anesthesia.

A

Harvey Cushing

187
Q

“No operation be undertaken unless the services of a skilled anesthetizer are available.”

A

Charles Frazier

188
Q

Father of neuroanesthesia

A

John D. (Jack) Michenfelder

189
Q

Performed Dämmerschlaff or “Twilight Sleep using morphine and scopolamine?

A

Richard von Steinbüchel

Morphine 10 mg + scopolamine then scopolamine on subsequent injections

190
Q

Blood transfusion was first attempted to?

A

Louis XIV, Jean Baptiste Denis

191
Q

The first American organization was founded by nine members on?

A

October 6, 1905

192
Q

The first American organization of anesthesiology was called? With annual dues of?

A

Long Island Society of Anesthetists

1 USD

193
Q

The first American organization of anesthesiology had initially how many members?

A

70

194
Q

He became editor of the first journal devoted to anesthesia, Current Researches in Anesthesia and Analgesia, the precursor of Anesthesia and Analgesia, the oldest journal of the specialty.

A

Francis Hoffer McMechan

195
Q

Helped establish the Australian Society of Anesthesiologists?

A

Geoffry Kaye

196
Q

What year, first time, physicians were recognized as specialists in anesthesiology?

A

1935

197
Q

Who was the first American to acquire an academic position in anesthesia?

A

Ralph Waters

198
Q

Organized the Anaesthetists’ Travel Club

A

John Lundy

199
Q

Who was the first president of the American Society of Regional Anesthesia?

A

Emery Rovenstein

200
Q

When was the American Board of Anesthesiology (ABA) organized as a subordinate board to the American
Board of Surgery?

A

1938

201
Q

When was the independence of AMA from ABA granted?

A

1940

202
Q

“An Anesthetist is a technician and an Anesthesiologist is the specific authority on anesthesia and anesthetics.
I cannot understand why you do not term yourselves the American Society of Anesthesiologists.”

A

Dr. M. J. Seifert

203
Q

Was declared the first president of the newly named ASA in 1945.

A

Ralph Waters

204
Q

How many ASA members were in the armed forces?

A

739 (37%)

205
Q

ASA’s first Distinguished Service Award was given to?

A

Paul M. Wood

Park Ridge, Illinois

206
Q

What year was the evolution of critical care progressed through the use of mechanical ventilators started?

A

1960