Intrapartum: Pre-Term, PROM, PPROM, Prolonged Flashcards
Define pre-term labour
Labour before 37W
What are 5 risk factors for pre-term labour
- Previous pre-term
- Miscarriage
- Multiple pregnancy
- Uterine anomalies
- Pre-eclampsia
If associated with cervical weakness, how may pre-term labour present
Bulging membranes
Vaginal discharge
Abdominal pain
If associated with infection, how may pre-term labour present
Pain
Fever
Pain
What investigations is important for pre-term labour
Foetal fibronectin
USS
What should be given if pre-term labour
IM Corticosteroids (betamethasone)
What dose of corticosteroids are given
12mg/24h
What is the advantage of corticosteroids
Reduce respiratory distress syndrome, intra-ventricular haemorrhage
What may be considered if pre-mature labour
Tocolytics
If labour is confirmed what should be given
Magnesium
IV Antibiotics
Why is magnesium (4g) given
To reduce risk cerebral palsy
Define pre-mature rupture of membranes (PROM)
Rupture of membranes one hour prior to labour in foetuses more than 37W
What is pre-term pre-mature rupture of membranes (PPROM)
Rupture of membranes one hour before labour in foetus less than 37W
What increases risk of PPROM
Smoking
What increases risk of PROM
Uterine anomalies Cervical weakness Previous PROM Polyhydramnios Infection Amniocentesis
How will PROM present
‘Waters break’ = ‘pop’ followed by water
Explain vaginal examinations in women with PROM labour
Do not perform a vaginal exam until confirmed women is in labour, Otherwise this increases risk of ascending infection which may cause women to enter labour quicker than if otherwise
How is diagnosis or PROM usually made
Clinically
What should be taken in all women with PROM
High vaginal swab to exclude group B streptococcus
What is fernig test and what can it be used for
Cervical discharge smeared on glass slide - if positive fern shape will be present. Can be used to confirm ROM
What can be looked for in secretions to determine if membranes ruptured
IGFBP-1
What typically happens to women with PROM
Enter labour 24-48h later
If PPROM happens before 33W what is done (4)
- Monitor for chorioamnionitis
- Avoid sexual intercourse
- Erythromycin
- Corticosteroids
If PPROM happens 34-36W what is offered (6)
- Monitor chorioamnionitis
- Erythromycin
- Swab for group B strep - if positive give clindamycin in labour
- Steroids (34 - 34+6W)
- IOL
If PROM happens >37W what is done
- Monitor chorioamnionitis
- Clindamycin if GBS isolated
- Wait 24h. If nothing, IOL
How long can women wait after PROM to spontaneously enter labour
96h
What is main complication of PROM
Chorioamnionitis
What other complication can PROM lead to
Oligohydramnios causing pulmonary hypoplasia
What is neonatal respiratory distress syndrome
Lung disorder due to deficiency in surfactant
What is the main risk factor for respiratory distress syndrome
Pre-maturity
What maternal condition can increase the risk of neonatal respiratory distress syndrome
Diabetes mellitus
How will neonatal respiratory distress syndrome present clinically
Onset of grunting at birth
What is the role of surfactant
Reduces alveolar surface tension - keeping them open
When does surfactant production occur
24W
When is surfactant distributed throughout the lungs
28W
When does surfactant reach sufficient concentrations and what does this mean
35W. Babies born before this (pre-mature) are at risk of respiratory distress syndrome
What is used to prevent neonatal respiratory distress syndrome
Antenatal corticosteroids
What is used to manage neonatal respiratory distress syndrome
Endotracheal surfactant
Oxygen (85%) increase gradually
What defines prolonged pregnancy
Pregnancy lasting >42W
What increases risk prolonged pregnancy
Previous history
FH
Maternal age >40
What is offered at 41W in prolonged pregnancy
Membrane sweep
What is offered at 41-42W in prolonged pregnancy
IOL
What are risks of prolonged pregnancy
Meconium aspiration IUGR Foetal distress Perinatal mortality Oiligohydramnios
What is foetal post-maturity syndrome
Used to describe post-term infants that present with malnutrition
How will babies with foetal post-maturity syndrome present
Scaphoid abdomen
Little SC Fat
Peeling skin over hands and feet