Intracerebral Hemorrhage Stroke Patho

Question 1

What is an ICH?

Answer 1

Occurs as a result of a cerebral blood vessel abnormally opening spilling blood into brain tissue.

Question 2

In an ICH, tissue damage and cell death occur via 2 pathways

Answer 2

Primary and secondary brain injury

Question 3

What is primary brain injury?

Answer 3

Cell injury that results directly from pressure incurred from hematoma formation.

Question 4

Deficits seen in the first several minutes to an hour are related to

Answer 4

Primary brain injury

Question 5

When is secondary brain injury seen after an ICH?

Answer 5

Hours to days after

Question 6

During the secondary brain injury, damage to cell membranes results in

Answer 6

An influx of electrolytes (ca++ and excitatory neurotransmitters) which causes necrosis and cytotoxic edema.

Question 7

During secondary brain injury a positive feedback loop causes

Answer 7

Cellular death, blood brain barrier disruption, vasogenic edema, and upregulation of inflammatory mediators.

Question 8

Name the types of hemorrhagic stokes

Answer 8

Subarachnoid
Intracerebral/intraparenchymal
Intraventricular

Question 9

Subarachnoid strokes are defined as

Answer 9

Bleeding into the subarachnoid meningeal space

Question 10

Intracerebral/intraparenchymal strikes are defined as

Answer 10

Bleeding into brain matter

Question 11

Intraventricular hemorrhagic strokes are defined as

Answer 11

Bleeding into the ventricles. Clots can form
High mortality
Associates with TBI