Intra- and Inter- molecular interaction

Question 1

Interactions with Amino acid residues

Answer 1

Amino acid residues on a peptide can interact non-covalently with other amino acid residues

Question 2

Intra-molecular interaction
(within the same peptide)

Answer 2

1)Intra-molecular interactions may also occur along the entire sequence of the polypeptide

2)This allows the polypeptide to bend at different parts into a folded configuration

3)Opposite charges on the side chains will attract
-like charges will repel
-hydrophobic side chains will group together

Question 3

Inter-molecular interaction
(across a different peptide)

Answer 3

1)Occurs between 2 or more peptides

2)The peptides will align themselves to fit the maximum interactions possible leading to a stable configuration