Intestinal Nematodes Flashcards

1
Q

Intestinal infection + anal pruritis (scotch tape test)

A

Enterobius vermicularis (pinworm)

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2
Q

E vermicularis transmission

A

food contaminated with eggs

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3
Q

E vermicularis Tx

A

bendazoles or pyrantel pamoate (worms are bendy; treat with mebendazole)

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4
Q

Intestinal infection onlly

A

Ascaris lumbricoides (giant roundworm)

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5
Q

Ascaris transmission

A

fecal oral-eggs visible in feces under microscope

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6
Q

Ascaris Tx

A

Bendazoles or pyrantel pamoate

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7
Q

Intestinal Infection+vomiting, diarrhea, anemia

A

Strongyloides stercoralis

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8
Q

Strongyloides transmission

A

larvae in soil penetrate skin

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9
Q

Strongyloides Tx

A

ivermectin or albendazole

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10
Q

intestinal infxn + anemia

A

Ancylostoma duodenale, Necator americanus (hookworms)

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11
Q

Ancylostoma/Necator anemia mechanism

A

suck blood from instestinal walls

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12
Q

Ancylostoma/Necator Tx

A

bendazoles or pyrantel pamoate

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13
Q

Ascaris epidemiology

A

US Southern mountains

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14
Q

Ascaris life cycle

A

Eat->hatch in intestine->invade->travel to lungs in blood->grow->coughed up, swallowed->new eggs hatch in intestine

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15
Q

Necator transmission

A

soil->penetrates skin as filariform larva after growing 1 week in soil

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16
Q

Most common Necator invasive site

A

between toes

17
Q

Necator life cycle

A

Skin->lungs->coughed up, swallowed->SI, adults attach with mouths, suck blood, and release eggs

18
Q

Strongyloides life cycle

A

Skin->lungs-> coughed up->SI->lay eggs

19
Q

Are Strongyloides eggs passed in stool?

A

No

20
Q

What are 3 actions Strongyloides filariform can do when hatch?

A

1) penetrate intestin, go to lung
2) pass out w/feces/ survive and maturate in soil, penetrate another (like Necator does)
3) replicate in stool, then come out mature and ready to infect

21
Q

‘Bend’ drugs

A

Mebendazole
Albendazole
Thiabendazole

22
Q

Bend with most AEs

A

Thiabendazole

23
Q

Bend MOA

A

paralyze parasite, which is passed in stool

24
Q

Abdominal pain, diarrhea, fever progressing to muscle ache

A

Trichenella spiralis

25
Q

T spiralis transmission

A

ingestion if larvae cysts

26
Q

What food are T spiralis cysts common in?

A

Raw pork

27
Q

T spiralis life cycle

A

ingestion->SI, maturation-> males into feces, females penetrate mucosa and produce larvae, which enter bloodstream and spread

28
Q

T spiralis Dx

A

serology, muscle biopsy (for larvae cysts)

29
Q

T spiralis CBC

A

lots of eos, inc CPK

30
Q

T spiralis Tx

A

mostly prevention (cook/freeze pork before eating). Bend drugs effective against enteric stage, but not against muscle stage