Intestinal Disorders Flashcards

1
Q

Inflammatory bowel dz types

A

Ulcerative colitis

Crohns Dz

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2
Q

IBD ethnic influence

A

More prominent in jews

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3
Q

IBD age

A

Mostly younger (10-30)

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4
Q

IBD patho

A

Defect in function of intestinal lumen.
Exposure of mucosa to bugs
T-cell mediated rxn

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5
Q

Systemic complications of IBD

A
apthous stomatitis
Uveitis
Arthritis
Vascular complications
Gallstones
Malabsorption
Kidney stones
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6
Q

Ulcerative colitis course (UC)

A

Flare ups and remissions
More common in nonsmokers
Sx may worsen in pts who stop smoking.
Higher risk for cancer.

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7
Q

UC S/S

A

Bloody diarrhea (at night)
Lower abd cramps
Fecal urgency
Can progress to fever, extreme pain, hypovolemia

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8
Q

Ulcerative colitis facts

A

Involves mucosal surface of colon, formation of crypt abscesses.
Alwats includes rectum, spreads proximally.
Uniform, no skip lesions

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9
Q

Ulcerative colitis labs

A

Anemia
Elevate sed rate
electrolyte disturbances
pANCA antibodies

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10
Q

UC dx

A

Best made w/ sigmoidoscopy
Bloody diarrhea
KUB
CT scan for complications

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11
Q

UC Tx

A

Sulfasalzine
Mesalamine
Prednisone

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12
Q

Crohn’s Dz

A

Transmural involvement w/ formation of fistulas, narrowing, obstruction.
Usually ileocolitis

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13
Q

What lifestyle choice is associated with crohns?

A

Smoking

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14
Q

Crohns dz usually spares the rectum

A

True

Differentiated from UC in that way

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15
Q

Crohns presentation

A
Insidious onset
Weight loss, pallor
Intermittent low grade fever, diarrhea, RLQ pain
Pain after meal
RLQ mass
Perianal dz
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16
Q

Which skin lesions may precede intestinal sx of crohns?

A

Erythema nodosum

17
Q

Crohns lesions

A

They are segmented and skip.
Are cobblestoned
Opposed to UC lesions, that are continuous.

18
Q

Perianal changes in crohns

A

Abscess
Fistula
Skin tag
Anal stricture

19
Q

ASCA test

A

Antibody test

Good to rule in, but lots of false negatives.

20
Q

String sign

A

Seen in crohns

21
Q

Crohns tx

A

Sulfasazine
Abx
Steroids
Infliximab

22
Q

Irritable Bowel Syndrome

A

Functional GI dz with variable recurrent or chronic sx not explained by structural or biochemical abnormalities
20% of pop
dx of exclusion

23
Q

IBS Dx

A

Continuous or recurrent sx for at least 3 months.
Abd pain, pain relieved by defecation.
Altered stool frequency, form, passage. Bloating, mucus

24
Q

Systemic sx of IBS

A
Fatigue
Back ache
Early satiety
Nausea
HA
Irritable bladder
25
Q

Does IBS usually cause sleep disturbance?

A

Nope

26
Q

IBS age range

A

Usually younger people

27
Q

T or F: Ulcerative colitis often involves the small bowel as well.

A

False, UC is only on the large bowel.