Interleukin Receptor Antagonist

Question 1

Interleukin Receptor Antagonist Drug Names

Answer 1

Analinra

Question 2

Interleukin Receptor Antagonist Therapeutic Actions

Answer 2

• Used to treat rheumatoid arthritis
• Block activity of interleukin-1
• Works to block the activity of the interleukins that are released in an inflammatory or immune response

Question 3

Interleukin Receptor Antagonist Indications

Answer 3

• Used to treat rheumatoid arthritis

- Block activity of interleukin-1

Question 4

Interleukin Receptor Antagonist Contraindications and Cautions

Answer 4

Contraindications:
• Known allergy to Escherichia coli–produced products or to anakinra
• Pregnancy and lactation
• renal impairment
• immunosuppression or any active infection

Question 5

Interleukin Receptor Antagonist DDI

Answer 5

DDI:

• Etanercept may cause severe and even life-threatening infections

Question 6

Interleukin Receptor Antagonist Adverse Effects

Answer 6

• Headache, sinusitis, nausea, diarrhea

the most common effects

Question 7

Interleukin Receptor Antagonist:

Assessment

Answer 7

Assess:
Hx: Contraindications and cautions
Physical: vital signs, weight, temp, orientation and reflexes (baseline)
Labs: baseline ECG

Question 8

Interleukin Receptor Antagonist:

Diagnosis

Answer 8

Dx:

• Acute pain: to CNS, GI and flu-like effects
• Risk for infection related to immune suppression
• Imbalanced nutrition: less than body requirements, related to nausea and vomiting
• Deficient knowledge: drug therapy

Question 9

Interleukin Receptor Antagonist:

Implementation

Answer 9

Implementation:
• Arrange for laboratory tests before and periodically during therapy
• Administer the drug as indicated; instruct the patient and a significant other if injections are required
• Protect the patient from exposure to infections and maintain a strict aseptic technique for any invasive procedures
• Monitor nutritional status during therapy; provide small, frequent meals, mouth care, and nutritional consultation
• Instruct females in use of barrier contraceptives
• Suggest another method of feeding the baby
• Provide thorough patient teaching

Question 10

Interleukin Receptor Antagonist:

Evaluation

Answer 10

Eval:
Response to the drug 
Adverse effects 
Effectiveness of comfort measures Compliance with the regimen
Effectiveness of the teaching plan