Interferons Flashcards
Mechanism of interferons
Glycoproteins synthesized by virus-infected cells that prevent protein synthesis of viruses
Types of interferons
IFN-alpha, IFN-beta, IFN-gamma
Indication for IFN-alpha
Chronic hepatitis B and C, Kaposi sarcoma, hairy cell leukemia, condyloma acuminata, renal cell carcinoma, malignant melanoma
IFN used for hepatitis B and C
IFN-alpha
IFN used for Kaposi sarcoma
IFN-alpha
IFN used for hairy cell leukemia
IFN-alpha
IFN used for condyloma acuminata
IFN-alpha
IFN used fro renal cell carcinoma
IFN-alpha
IFN used for malignant melanoma
IFN-alpha
Indication for IFN-beta
Multiple sclerosis
IFN used for multiple sclerosis
IFN-beta
Indication for IFN-gamma
Chronic granulomatous disease
IFN used for chronic granulomatous disease
IFN-gamma
IFN side effects
Flu-like symptoms, depression, neutropenia, myopathy