Interferons Flashcards

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1
Q

Mechanism of interferons

A

Glycoproteins synthesized by virus-infected cells that prevent protein synthesis of viruses

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2
Q

Types of interferons

A

IFN-alpha, IFN-beta, IFN-gamma

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3
Q

Indication for IFN-alpha

A

Chronic hepatitis B and C, Kaposi sarcoma, hairy cell leukemia, condyloma acuminata, renal cell carcinoma, malignant melanoma

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4
Q

IFN used for hepatitis B and C

A

IFN-alpha

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5
Q

IFN used for Kaposi sarcoma

A

IFN-alpha

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6
Q

IFN used for hairy cell leukemia

A

IFN-alpha

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7
Q

IFN used for condyloma acuminata

A

IFN-alpha

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8
Q

IFN used fro renal cell carcinoma

A

IFN-alpha

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9
Q

IFN used for malignant melanoma

A

IFN-alpha

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10
Q

Indication for IFN-beta

A

Multiple sclerosis

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11
Q

IFN used for multiple sclerosis

A

IFN-beta

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12
Q

Indication for IFN-gamma

A

Chronic granulomatous disease

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13
Q

IFN used for chronic granulomatous disease

A

IFN-gamma

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14
Q

IFN side effects

A

Flu-like symptoms, depression, neutropenia, myopathy

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