Integumentary System Flashcards
All parts of the integumentary system
Skin
Hair
Skin glands (sebaceous, sudoriferous)
Nails
Skin
Largest organ in the body (surface area and weight)
Ranges from 0.5mm (eyelids) to 4.0mm (heels) thick
Has 2 layers
Epidermis – superficial layer, thin, epithelial tissue
Dermis – deep layer, thicker, connective tissue
Epidermis –
superficial layer, thin, epithelial tissue
dense and highly packed skin cells
Dermis –
deep layer, thicker, connective tissue
The dermis is attached to the underlying fascia by a subcutaneous layer of areolar and adipose tissues
Top layer of skin
Epidermis
middle layer of skin
Dermis
Deep layer of skin
subcutaneous layer
Epidermis – Cell Types
Keratinocytes
Langerhans cells
Merkel cells
Melanocytes
Keratinocytes
~90% of epidermal cells
Produce keratin (tough, fibrous protein) and lamellar granules (release water-resistant lipids)
Langerhans cells
Migrate to the epidermis from red bone marrow
Contribute to the body’s immune responses
Merkel cells
Located in the deepest layer of the epidermis
Contact specific sensory receptors (Merkel discs) that detect touch sensations
Melanocytes
Produce melanin (pigment that absorbs UV light)
Slender projections transfer melanin to keratinocytes
Epidermis – Structure
The epidermis has 4-5 layers of keratinocytes in various stages of development
“Thin skin” (4 layers) – covers most of the body
“Thick skin” (5 layers) – covers areas exposed to friction
(e.g., palms of the hand, soles of the feet)
Keratinocytes are formed in the deepest layer and slowly get pushed to the surface
They accumulate more keratin as they proceed and eventually undergo apoptosis (programmed cell death) before being sloughed off
Stratum Basale
Single row of columnar keratinocytes that act as stem cells (continually undergo cell division to produce new cells)
in the deepest layer of the skin
Stratum Spinosum
8-10 layers of many-sided keratinocytes
middle area of the skin
Stratum Granulosum
3-5 layers of flattened keratinocytes that undergo apoptosis
Production of keratin and lamellar granules
right above the middle of skin