Integumentary system Flashcards
Largest organ
External covering of the body
Continuous with the mucous membranes at points of transitions (_____ _____)
SKIN
mucocutaneous junctions
mucocutaneous junctions of the digestive system (2)
lips, anus
mucocutaneous junctions of the respiratory system
nose
mucocutaneous junctions of the Urogenital system
external orifices
mucocutaneous junctions that is continuous with the conjunctiva
Eyelid
FUNCTIONS OF THE SKIN (5)
- Protective
- Sensory
- Thermoregulatory
- Metabolic
- Sexual signaling
2 main layers of the skin
Epidermis
Dermis
Epidermis and dermis interdigitate with each
other by the formation of: (2)
Epidermal ridges
Dermal papillae
2 classifications of skin
Thick skin - sole and palm
Thin skin
Layers of the epidermis of thick skin (5)
Stratum corneum
Stratum lucidum
Stratum granulosum
Stratum spinosum
Stratum basale
Cornified cell layer
Most superficial layer
Composed of several layers of dead, flattened _______ (squames)
Stratum corneum (thick skin)
keratinocytes
Clear cell layer
Poorly stained keratinocytes filled with _____ and ______
Stratum lucidum (thick skin)
keratin
eleidin
Granular cell layer
Polygonal-shaped nucleated keratinocytes with coarse, basophilic keratohyalin granules in the cytoplasm
Stratum granulosum (thick skin)
Prickle cell layer
Thickest layer of the epidermis
Composed of mitotically active and maturing polygonal keratinocytes (____ ____) that interdigitate with one another by forming intercellular bridges
Stratum spinosum (thick skin)
prickle cells
Stratum germinativum
Deepest layer of the epidermis
Single layer of mitotically active, cuboidal to low columnar cells containing basophilic cytoplasm and a large nucleus
Stratum basale (thick skin)
What makes up the Malpighian layer?
Stratum spinosum + Stratum basale
Only about 5 layers of squames
Stratum corneum (thin skin)
what layer of the epidermis is combined in think skin?
Stratum lucidum, Stratum granulosum
Same as in thick skin but layers are reduced
Stratum spinosum (thin skin)
stratum basale of thin skin is the same as thick skin: true or false
true
DISTINCT CELLS IN THE EPIDERMIS (4)
Keratinocytes
Melanocytes
Langerhans cells
Merkel cells (Tactile epithelioid cells)
Most predominant
Their morphology that is responsible for the
characteristics of the five layers
Vary in size and shape and differentiate as they migrate upward to form keratin
Keratinocytes
Derived from neural crest cells
Produce melanin
Found in stratum basale
Melanocytes
Intraepidermal macrophages
Derived from bone marrow
Function as antigen-presenting cells in immune responses
Found in stratum spinosum
Langerhans cells
Probably derived from neural crest
Function as mechanoreceptors
Found in stratum basale
Merkel cells (Tactile epithelioid cells)
structure that is Beneath the epidermis
DERMIS or corium
2 layers of dermis
Papillary layer
Reticular layer
Loose connective tissue
Interdigitates with the epidermis
Papillary layer of dermis
Irregular DWFCT
Main and deeper part
Also contains epidermally derived structures, including sweat glands,
hair follicles, and sebaceous glands
Reticular layer of dermis
sensory receptors that can be found in reticular layer of dermis (3)
Pacinian corpuscle
Ruffini’s corpuscles
Krause’s end bulbs
Perceive pressure and vibration
Pacinian corpuscle of dermis
Reacts to tension placed on skin
Ruffini’s corpuscles of dermis
Believed to function as mechanoreceptors
Krause’s end bulbs of dermis
Beneath the dermis
Anchors the dermis to the underlying muscle or bone
Loose connective tissue
With adipose cells
HYPODERMIS
May form adipose cells:
Small clusters
Large masses (cushion or pad of fat)
Panniculus adiposus
HYPODERMIS
ASSOCIATED STRUCTURES IN THE SKIN
Hair
Covers the body
Flexible, keratinized structure produced by a hair follicle
Hair
PARTS OF THE HAIR (8)
Hair bulb
External root sheath
Internal root sheath
Glassy membrane
Dermal root sheath
Cuticle
Cortex
Medulla
Hair bulb is made up of
Hair root
Dermal papilla
expanded terminus
Hair root
vascularized connective tissue
core
Dermal papilla
Downgrowth of epidermis; several
layers
External root sheath
Internal root sheath 3 layers
Henle’s layer (outer): single row of
cuboidal cells
Huxley’s layer
Cuticle of internal root sheath
Non-cellular hyaline layer
Separates the dermis from the
epithelium of the hair follicle
Glassy membrane
Composed of collagen and elastic fibers
richly supplied by blood vessels and
nerves
Dermal root sheath
Thin layer of heavily keratinized,
squamous cells
Covering the cortex
Cuticle
Heavily keratinized, densely packed
cells
Surrounds the medulla
Cortex
Have large, vacuolated, and
moderately keratinized cells
Forms the center
Medulla