Integumentary system Flashcards
what is the name for skin
cutaneous
what is the largest organ
skin
how thick is skin
o.5mm on the eyelids and 4.0 mm on the heels
Epidermis
Superficial layer, thin, epithelial tissue. Densly packed layers of cells and appears darker
Dermis
Deep layer, thicker, connective tissue. very few cells and composed of collagen and elastic fibers
What is the dermis attached to?
The underlying fascia by a subcutaneous layer of areolar and adipose tissues
keratinocytes
90% of epidermal cells, produce keratin and lamellar granules and a barrier
lamellar granules
release water-resistant lipids
keratin
tough, fibrous protein
Langerhans cells
Migrate to the epidermis from red bone marrow and contributes to the bodys immune responses
Merkel cells
In the deepest layer of epidermis and hare contact specific sensory receptors (merkel discs) that detect touch sensations
Melanocytes
in the deepest layer of epidermis, produce melanin and slender projections transfer melanin to keratinocytes
How many layers in epidermis
4-5 layers of keratinocytes in various stages of development
Thin skin
4 layers, covers most of the body
thick skin
5 layers, covers areaas exposed to friction (palms, soles)
kerationcytes formed where
Formed in the deepest layer and slowly get pushed to the surface. They accumulate more keratin as the proceed and eventually undergo apoptosis before being sloughed off
Apoptosis
programmed cell death
Stratum basale
Single row of columnar keratinocytes that act as
stem cells
(continually undergo cell division to produce new cells)
Stratum Spinosum
Superficial to stratum basale. 8-10 layers of many-sided keratinocytes
stratum granulosum
superficial to stratum spinosum. 3-5 layers of flattened keratinocytes that undergo apoptosis. Production of keratin and lamellar granules
Stratum lucidum
4-6 layers of clear, flat, dead keratinocytes that have large amounts of keratin. Only in thick skin
Stratum corneum
Most superficial, 25-30 layers of flat dead keratinocytes that contain mostly keratin that are pushed to the skins surface. Superficial layers are continally sloughed off and replaced