Integumentary System Flashcards
Integumentary System
Skin and it’s accessory structures (grow from the skin)
Accessory structure: hair, nails, glands
Dermatology
The study and treatment of the integumentary system
Skin
Our largest organ combined of two tissue types; epithelial and connective
Epidermis layer is made of what tissue
Stratified-Squamous Epithelial Tissue (waterproof/ tough)
Dermis layer is made of what tissue
Areolar connective tissue and Dense irregular CT
Hypodermis layer is made of what tissue
Adipose CT (mostly) + areolar CT
Epidermis
4-5 main layers:
Stratum-
• Corneum “Can Lucy give some blood”
• Lucidum
• Granulosum
• Spinosum
• Basal
Epidermis main cell type in all layers
Keratinocytes- cells that move keratin protein (gives skin strength/toughness & waterproofs the skin)
Stratum Basal
Deepest layer: one row of cells
Connected to the basement membrane along “wavy line”
Stratum Basal components
Mostly keratinocytes: undergo mitosis constantly & gets pushed up
Some merkel cells: sensory cells for touch
Some Melanocytes: skin pigment cells
Stratum Spinosum
Thickest layer (many rows)
Mostly Keratinocytes pushed up from the stratum basal.
Begins production of keratin protein
Some Dendritic cells: immune cells that phagocytose bacteria debris and damaged cells
Stratum Granulosum
3-5 rows of cells
Keratinization occur in this layer
⬆️Keratinocytes fill up w/so much keratin protein that they die
Stratum Lucidum
Dead layer
Only in thick skin- thick as paper towel (hand/feet only)
Thin skin- thin as printer paper ⬆️(everywhere else)
Stratum cornuem
Dead scaley layer (many rows thick)
Not cells anymore
Just keratin protein cover in PM
Shed and replace every 4 wks
Melanin
Main skin pigment molecule
Made by melanocyte cells in stratum basal
Protects skin cell DNA from damage