Integumentary Flashcards
What is the goal of inflammation? (vascular response)
Control bleeding, fight infectious agents
- transudate leaks out of vessels: local edema
- local blood vessesl contrict
- 30 minutes of vasocontriction, vasodilation occurs: localized redness, warmth, edema
Cardinal Signs of inflammation
Edema, redness, warmth, pain, decreased function
What are the key cells in inflammation?
- Polymorphonuclearnutrophils (PMNs) to sides of vessel walls
First to site of injury 12-24 hours, kill bacteria, clean wound, secrete matrix
- Macrophages: kill pathogens, direct repair process
- Mast cells: produce histamine and secrete enzymes to accelerate riddance of damage cells
(PPMM)
Key cells in proliferation
- Angiogenesis: formation of new blood cells (angioblasts)
- Granulation tissue - FIBROBLASTS lay down extracellular matrix (eventually replaced by scar tissue)
- Wound contraction - myofibroblasts pull wound margins together
- Epithelization - karatinocytes and epidermal appendages multiply and migrate across wound bed
Maturation Phase
- Granulation tissue strengthened and reorgainzed
- Rapid collagen synthesis
2 year following would closure 6-12 months greatest change
- 80% of full strength tissue
- Unable to sweat, less sensetive to touch and temp
What is an example of a systemic factor?
Age
- slowed immune response
- decreased collagen synthesis
Epidermal and dermal atrophy
less sweat
Decrease pain perception
Nutrition
Comorbidities
Affect O2 perfusion - PVD, anemia, COPD
Medications
Behavioral risks
Smoking
Primary (Primary intention) Would closure
Wound edges are approximated without/little formation of granulationtissue
Not seen by PT typically
Secondary (secondary intention) wound closure
- Wound edges unable to be approximated
Granulation tissue fills wound bed (scar tissue)
PT more likely to be involved
What can lead to eschar formation and necrosis?
Low moisture levels
D I M E
Debridement
Inflammation/infection - stage of healing, infection, phase of healing
Moisture Balance - tissue type, immunocompromised, activity infection, out of proportion for phase of healing
Edge effect - progressing/stage rolled, callus clean
Local wound care and assessment
HEALABLE - Address underlying cause
Granulation tissue
Temporary scaffolding of vascularized conenctive tissue, healthing granulation is bright beefy red; if pale or dusky, blood supply may be poor or may be infected
Necrotic/Non-Viable tissue
Slough - yellow or tan, stringy or mucinous
Eschar - black and nectroic tissue,
Fascia, adimpose, muscle, tendon, joint, bone, new epithelium
Undermining
Tissue under wound edge is gone, similar to cave under skin
Serous Drainage
Protien rich fluid WBC
Clear-Pale yellow, watery
Sanguinous
Blood/Drying blood
Red/dark brown