Integumentary Flashcards
Integumentary System
Structures:
● Skin
● Hair
● Nails
● Glands
- Superficial layer of keratinized stratified squamous
epithelial tissue - Avascular (there are no blood vessels present)
- Composed of epithelial cells arranged into layers or
strata - Separated from dermis by basement membrane
- Protect against the potential damage from abrasion on the
skin’s surface - Not as thick as the dermis
Epidermis
produce a protein mixture called keratin (makes
cells more durable)
- durability of keratinocytes gives the epidermis
its ability to resist abrasion and reduce water loss - constantly lost at its surface but are also
constantly replaced by new keratinocytes moving from deeper
layers
Keratinocytes
produce the pigment melanin, which contributes to
skin color
Melanocytes
- 2-5 layers of somewhat flattened, diamond-shaped cells
- there is a presence of protein granules of keratohyalin which
accumulate in the ctyoplams of keratinocytes - lamellar bodies move to the plasma membrane and release lipid
contents - nucleus and other organelles degenerate in superficial layers
Stratum Granulosum
thin, clear zone of dead keratinocytes with indistinct
boundaries
- found only in palms and soles
- cells appear somewhat transparent
- present only in thick skin
Stratum Lucidum
consists of 25 or more layers of dead, overlapping squamous
cells joined by desmosomes called cornified cells (dead
keratinocytes with a hard protein envelope)
- cell remnants have a soft protein envelope of keratin
Stratum Corneum
8-10 layers of many-sided cells and as the cells in this
stratum is pushed up, it flattens (desmosomes break apart)
- additional keratin fibers and lipid-filled, membrane-bound
organelles called lamellar bodies form inside the cells
Stratum Spinosum
deepest portion and is a single layer of cuboidal or columnar
cells
- the epidermis is anchored to the basement membrane
- high mitotic activity in keratinocytes which undergo mitosis
every 19 days
Stratum Basale
- provides protection against UV light
- derived from tyrosine
- primarily responsible for skin, hair, and eye color
Melanin
deposit melanosomes and produces melanin
Melanocytes
deficiency or absence of pigment
Albinism
- yellow pigment from vegetables, source of vitamin A
- accumulates in stratum corneum, adipose cells and
subcutaneous tissue
Carotene
red color caused by increased blood flow
Erythema
- Gives structural strength, C.T. with many fibers
- Contains nerves, blood vessels, hair follicles, smooth muscles,
glands, and lymphatic vessels - Sensory functions: pain, itch, tickle, temperature, touch,
pressure, two-p
Dermis