Insulinas Flashcards

1
Q

Insulinas ultra rapidas cortas

A

Lispro
Aspartica
Glulisina

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2
Q

Insulina rápida corta

A

Regular (cristalina, humana)

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3
Q

Insulinas largas prolongadas

A

Glargina
Degludec
Detemir

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4
Q

Insulina larga intermedia

A

NPH (neutra de hagedron)

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5
Q

Afinidad al receptor IGF1
Idéntica a la humana excepto en b28 y b29

A

Lispro

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6
Q

Administración de cortas

A

Subcutánea
Se dan 15 min antes de comer
Glulisina única en bomba

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7
Q

EA
cortas

A

Hipoglucemia
Aumento peso
Lipohipertrofia

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8
Q

Intercambia b28 prolina por ac aspartico

A

Aspartica

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9
Q

Lisina y arpagina por ac glutamico

A

Glulisina
Única en bomba subcutánea

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10
Q

TX gastroparesia diabetica

A

Glulisina

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11
Q

Causa menos hipoglucemia nocturna

A

Aspartica

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12
Q

Obtenida del ADN de E. Coli

A

Regular

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13
Q

VA
Insulina regular

A

Subc, IV, IM > 100 u/ml
Solo sub > 500 u/ml

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14
Q

Administrar 30-45 min antes de comer

A

Regular

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15
Q

Es la de elección para embarazadas y hospitalizados

A

Regular

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16
Q

Emergencia para cetoacidosis y estado hiperglucemico hiperosmolar

A

Regular

17
Q

Tiene zinc + portaminas
Turbia y lechosa
Administrada antes de dormir

A

NPH

18
Q

Reduce la hiperglucemia en ayuna en DM2

A

NPH

19
Q

EA de NPH

A

Es la q causa más hipoglucemia

20
Q

LARGA
Glicina por aspargina

A

Glargina

21
Q

Administradas 1 vez al día por la noche

A

Glargina
Degludec

22
Q

Adm 1-2 veces al día a la misma hora
Subcutánea

A

Detemir

23
Q

Ultra lenta (48hr)
Se da con metformina para evitar hipoglucemia

A

Degludec

24
Q

EA
DEGLUDEC

A

Lipoatrofia

25
Q

Es la que causa menos aumento de peso
LARGA

A

Detemir
Para DM1