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Farma > Hipolipemiantes > Flashcards

Hipolipemiantes Flashcards

1
Q

Familias

A

Estatinas
Resinas anionicas
Ac fibrico / fibratos
Anticolesterol
Vit B3

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2
Q

Estatinas (vastatinas)

A

Lovastatina
Ator
Rosu
Pra
Sim
Flu
Pit

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3
Q

Resinas anionicas

A

Colestiramina + colestipol
Colesevelam

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4
Q

Ac fribrio / (fibratos)

A

Clofibrato
Cipo
Beza
Feno
Gem

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5
Q

Antagonistas del colesterol

A

Ezetimibe
Orlistat

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6
Q

Vit B3

A

Niacina

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7
Q

MAC
Estatinas

A

Inhiben HGM-CoA reductasa
Reducen LDL, colesterol, VDL
Aumentan HDL

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8
Q

ADMR
Estatinas

A

VO
Excreción biliar
Metabolismo hepático
Adm 1 - 2 hrs antes de dormir

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9
Q

Función
Estatinas

A

Prevención de ECV tipo isquemico
Sinergia con resinas, niacina o ezetimibe
Niños con hipercolesterolemia fam

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10
Q

EA
Estatinas

A

Miopatia por aumento de rabdomiolisis
Hepatotoxicos
Aum incidencia DM2 en prediabeticos

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11
Q

CI
Estatinas

A

Embarazadas
NO USAR CON FIBRATOS
hepatopatas

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12
Q

Tx de hipercolesterolemia INTENSA
+ rosu
SV LARGA 20h

A

Atorvastatina

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13
Q

Tx indicado en niños mayores de 8 años

A

Pravastatina

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14
Q

Profarmaco de Lactona

A

Lovastatina

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15
Q

MAC
Resinas anionicas

A

Secuestran ac biliares e inhiben su abs
Disminuyen LDL
Combinadas con estatinas xq resinas aumentan TAG

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16
Q

Función
Resinas

A

2 LINEA PARA REDUCIR LIPIDOS

Usado entre 11-20 años
Embarazadas

17
Q

EA
Resinas

A

Meteorismo
Esteatorrea
Colelitios

18
Q

MAC
Niacina

A

Inhibe la lipolisis de TAG por la lipasa sensible a hormonas
Inhibe acetiltransferasa 2 de diacilglicerol
Aum HDL
Dism VLDL , LDL, LP

19
Q

Función
Niacina

A

Hipertrigliceridemias intensas
Hipercolesterolemia heterocigotica

20
Q

EA
Niacina

A

Rubor / hiperemia, se trata con aspirina
Hepatotoxicidad
Hiperuricemia

21
Q

MAC
Ac fibrico
Clo, cipro, beta, feno, gem

A

Agonistas del PPAR alfa
Dism trigliceridos

22
Q

Función
Fibratos

A

1 primera elección HIPERTRIGLICERIDEMIA AISLADA

HIPERTRIGLICERIDEMIA GRAVE >1000 mg/dl con RIESGO DE PANCREATITIS

23
Q

EA
Fibratos

A

Rabdomiolisis
Generan cálculos biliares

24
Q

Fibrato mas peligroso y útil en NEFROPATAS

A

Gemfibrozilo

25
Q

MAC
Antag colesterol
Ezetimibe

A

Inhibe proteína NPC1L1
Inhibe absorción de colesterol en enterocitos

26
Q

Usado para disminuir LDL en px que no tolerar las estatinas

A

Ezetimibe

27
Q

Alergia y miositis son su EA

A

Ezetimibe

28
Q

MAC
Inhibe la lipasa pancreatica
No metaboliza ac grasos libres

A

Orlistat

29
Q

Función orlistat

A

Tx Obesidad para controlar de peso
Produce esteatorrea

Farma (6 decks)

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