Inorganic Medicinals - Alkali Earth Metals Flashcards
Other Name for Hydrogen
“Inflammable Air”. “Flammable Air”
Lightest Element
Hydrogen
Isotopes of Hydrogen
(a) Protium -> most abundant
(b) Deuterium -> heavy hydrogen
(c) Tritium ->radioactive isotope
Lightest Metal/Bridge Element
Lithium
Pharmacologic action of lithium
Diuretic
“Mood-Stabilizing Agent”
Used in mania and bipolar manic- depressive illness
Use of Lithium Citrate USP
tx of hypomanic and manic stress
DOC for mania
Lithium Carbonate (LiCO3)
Use of Lithium Bromide
Used as sedative because of central DEPRESSANT properties of bromide ion
Most abundant Extracellular Fluid Cation
Sodium (Na)
Other name of sodium
Natrium
Components of Benedict’ Reagent
- Sodium Carbonate (Na2CO3)
- Sodium Citrate (Na2C6H5O7)
Components of Fehling’s Solution
- Potassium Sodium Tartrate (NaKC4H4O6)
- Sodium Hydroxide (NaOH)
Cation of choice to optimize the pharmaceutical utility of organic medicaments
Sodium
Use of Sodium Chloride (NaCl)
Electrolyte Replenisher
Caution for the Usage of Sodium
caution in the treatment of cardiac & renal condition in w/c edema is a problem (Fluid Retention)
Most abundant intracellular cation
Potassium
Very similar in behaviour to potassium
Rubidium
Catalyst in the polymerisation of resins
Cesium
Used in the density gradient centrifugation.
CsCl
Hypothetical alkali metal and its salts resemble K and Rb salts (isomorphous)
Ammonia
Give the therapeutic activity of each and other name: Ammonium Carbonate (NH4)2CO3; Ammonium Chloride NH4Cl; Ammonium Bromide NH4Br;
(1) Expectorant; Hart’s horn
(2) Expectorant; Muriate of Hartshorn
(3) Central Depressant
Reagents that will precipitate potassium
Sodium Cobaltnitrite
Tetraphenylboron
Perchloric Acid
Other name of Sodium Dihydrogen Phosphate (NaH2PO4) and use
Fleet Enema; Cathartic, Urinary Acidifier
Use of Sodium Bisulfite (NaHSO3)
Water soluble antioxidant
Use of Sodium Acetate (NaCH3COO)
Diuretic, urinary alkalinizer, Antacid
What test benedict’s solution is used?
Alkalinizing agent; test for ketone, aldehydes & reducing sugar
Cations in Triple Acetates of Sodium
Co
Zn
Mg
“Baking soda”is known as?
Sodium Bicarbonate (NaHCO3)
Use of NaHCO3
Systemic Antacid
Antidote for Zinc Poisoning
Sodium Bicarbonate
Side Effects of NaHCO3
Rebound Hyperacidity, Systemic Alkalosis, Enema
Use of Sodium Carbonate (Na2Co3)
Antacid, Carbonating Agents (Source for Carbonate Ion)
Known as Rock/Table/Solar Salt
Sodium Chloride (NaCl)
Use of NaCl
Electrolyte replenisher, Preservative, Condiment
Use of Sodium Citrate (Na3C6H5O7)
Anti-coagulate (due to citrate), Diuretic, Chronic Acidosis, Buffer, Alkalinizer, Expectorant
Side effects of Sodium Citrate (Na3C6H5O7)
Bleeding
Use of Sodium Flouride (NaF)
Anticariogenic (prevent dental caries)
Other name of Sodium Hydroxide (NaOH)
Caustic Soda,Lye
Use of NaOH
Saponifying agent; NaOH TS (Reagent used to differentiate mercurous salts from mercuric salts)
Other name of Sodium Hypochloride (NaClO)
Chlorox, Bleaching powder
Use of NaClO
Oxidizing Agent, Bleaching Agent
2 Kinds of Diluted Sodium Hypochlorite and Uses
(1) Modified Dakins Soln’ :
Antiseptic
(2) Dakins Solution:
Disinfectant
Use of Sodium Iodide (NaI)
Expectorant, Iodine Solubilizer, Antifungal
Use of Sodium Lactate (NaC3H5O3)
Antiketogenic, Electrolyte Replenisher, Antacid, Diuretic
Other name of Sodium Metaphosphate
Graham’s Salt
Use of Sodium Nitrite (NaNO2)
Vasodilator
Antidote for Cyanide Poisoning
NaNO2
Other name of Sodium Nitrate
Chile Salt Peter
Use of Sodium Nitrate
Meat Preservative
Other name of Sodium Sulfate
Glauber’s Salt
Use of NaSO3
Cathartic
Use of Sodium Tartrate (Na2C4H4O6)
Primary std for Karl Fisher Reagent (Method I- Water Determination)
Use of Sodium Thiocyanate (NaSCN)
Hypotensive
Other name of Sodium Thiosulfate (Na2S2O4)
Hypochlor, Photographer’s Hypo
Antidote for Cyanide poisoning with sodium nitrate
Sodium Thiosulfate
Use of Disodium Calcium (EDTA)
Used as stabiliser for silver protein compounds
Use of Sodium Metabisulfite
used when Sodium bisulfate is specified.
Process used to obtain 99% purity hydrogen
Messerschmidt process
Pharmacological Action of Potassium
Diuretic, Muscular Contraction
Use of Potassium Acetate (KCH3COO)
Diuretic, Urinary alkalinizer, Antacid,
Other name of Potassium Arsenite
Fowler’s Solution
Other name of Potassium Sulfate (KAl(SO4)2)
“Potassium Alum “, “Potash Alum”, “Tawas”
Use of Potassium Bicarbonate (KHCO3)
Systemic Antacid;
Carbonating Agent for effervescent prep. ; Source of Bicarbonate ion
Other Name of Potassium Bitartrate (KC4H5O6)
“Cream of Tartar”, “Creamor”
Use of Cream of Tartar
Laxative
Pharmacological Action of KBr
Depressant; Use for IR Analysis
Other name of Potassium Carbonate (K2CO3)
“Potash, “Salt of Peter”, “Pearl ash”
Use of Potash
Antacid, Carbonating Agent, Carbonate source
Also known as Bertholate Salt
Potassium chloride (KCLO3
Use of Potassium Chloride
Electrolyte Replenisher (Slow push) IV push : Lethal Injection
Use of Potassium Citrate
Diuretic, Expectorant, Diaphoretic
Caustic Potash is known as?
Potassium Hydroxide
Use of KOH
Saponifying agent (produces liquid/soft soap)
Use of Potassium Iodide (KI)
Expectorant, Iodine Solubilizer, Antifungal
Other name of Potassium Nitrate and use
“Salt Peter”, “Salt Prunelle”, “Salitre”
Use: Meat Preservatives
Known as Mineral Chameleon
Potassium Permanganate (KMnO4)
Use of KMnO4
Oxidizing Agent,
Primary Standard for KMnO4 VS: Sodium Oxalate
Secondary Standard: Oxalic Acid
Antidote for Strychnine Poisoning
KOH
Use of Potassium Dihydrogen Phosphate (KH2PO4)
Cathartic
Other name of Potassium Sodium Tartrate (KNa2C4H4O6)
“Rocehlle Salt”, “Sal Signette”
Use of Rochelle Salt
Cathartic, Sequestering Agent
Use of Potassium Thiocyanate (KSCN)
Hypotensive Agent
Known as Liver of Sulfur
Sulfurated Potash[K2SO4/(K2Sx)2]
Use in the tx of Psoriasis
Liver of Sulfur
Potassium tetraiodomercurate(II) (K2HgI4) is also known as?
“Nessler’s Reagent”
Use of “Nessler’s Reagent”
an alkaline solution used to detect Ammonia
Reagents that will ppt potassium?
- Sodium Cobaltinitrite
- Tetraphenylboron
- Perchloric Acid
Pharmacologic Action of Ammonium
Diuretic/Buffer/Expectorant/Anti-cardiogenic
Use of Ammonium Iodine (NH4Cl)
Source of iodide, Expectorant,
Antifungal
Another name of Ammonium Acetate (NH4CH3COO) and use
“Spirit of Minderesus”
Use: Buffer component
“Spirit of Sal Volatile”, “Spirit of Hart’s Horn” is known as?
Aromatic Ammonia Spirit
Use of Aromatic Ammonia Spirit
Respiratory Stimulant
Other name of Ammoniated Mercury (HgNH2Cl)
White Precipitate
Use of White ppt?
Topical Anti-infective
Used to separate Bismuth from copper & cadmium
Ammonium Hydroxide
Different Ammonium Complexes
- Copper - Blue
* Cadmium - Colorless *Bismuth - white hydroxide