Innate to adaptive

Question 1

Cell comm

____used for comm
induce changes such as growth, differentiation movement or cell death

Answer 1

cytokines

Question 2

Cytokines:types

what are the 4 types of cytokines

Answer 2

Chemokines
Interferons
Interleukins
Tumor necrosis factor

Question 3

Cytokines:types

fill the blanks

Answer 3

chemokines
Interferons
Interleukins
Tumor necrosis factors

Question 4

Cytokines:chemokines

Impo In___of immune cells

Answer 4

Chemotaxis

Question 5

Cytokines:Interferons

_____proteins
impo role in control of____infections
also help regulate cells involved in____response

Answer 5

glycoproteins
viral infections
Immune

Question 6

CYtokines:INterleukins

impo in____&___immunity,______

Answer 6

Innate adaptive inflammation

Question 7

cytokines:tumor necrosis factor

help kill___cells
initiate_____

Answer 7

tumor cells
apoptosis

apoptosis:programmed cell death

Question 8

lymphocyte subsets

guess the subsets

Answer 8

B cell
helper T cell
cytolytic T cell
NK cell

Question 9

Natural killer cells

source:_____precursors
cytotoxic for
____cells
_____infected cells
other microorganisms

Answer 9

bone-marrow
tumor cells
viral infected cells

Question 10

Natural cells

charateristic markers:CD___&___
T-cell markers:CD__,__,__
activated by cytokines:IF___,____,____ which causes IFN gamma secretion
do not carry__or__cell receptors
receptors both___&____

Answer 10

CD16&56
CD3-,4-,8-
IL-12,15,18
do not carry T or B cell receptor
both inhibitory & activatory

Question 11

natural killer cells

IF-12,15 and 18 are NK cell____receptors

Answer 11

marker

Question 12

IFN__&___causes Interferon response

Answer 12

alpha and beta

Question 13

NK cell receptors:Inhibitory receptors

fill the blanks

Answer 13

normal cell
HLA-class I molecules
CD8+

Question 14

Nk cell receptors:activatory receptors

recognize____or____antigens

Answer 14

virus or tumor

Question 15

NK cell recognition:recognition patterns

fill the blanks

Answer 15

HLA-class I
NKG2D
antibody-dependant cell-mediated cytotoxicity

Question 16

NK cells can attack tumor cells lacking____expression

Answer 16

HLA class I

Question 17

NK cells prolong survival, but cannot prevent____

Answer 17

death

Question 18

NKT cells

T-cells that have____cell marker(CD3+,CD56+)
release cytokines____&___after activation

Answer 18

Natural killer cell marker
IFN gamma & IL-4

Question 19

gamma-delta T cells

part of first line of____defence
mature in___
found as_____lymphocytes
mostly in gut & oral mucosa

Answer 19

innate defence
intra-epithelial lymphocytes

Question 20

gamma-delta T cells

recognize antigens other than____associated peptides(unlike CD_or_cells)
also works on___based antigens

Answer 20

HLA-associated
CD4+orCD8+ cells
works on lipid based

Question 21

dendritic cells

develop in bone marrow from progenitor(CD_)cells or monocytes(CD__)
mostly found___of cell

Answer 21

CD34+ CD14+
enterance of cell

Question 22

dendritic-cell maturation

epidermal dendritic cells are called____cells

Answer 22

langerhans

Question 23

dendritic cells

which one is mature/Immature

Answer 23

Immature mature

Question 24

Dendritic cells-major subtypes:myeloid dendritic cells

CD___,___
____marker
mainly in____tissues
major cytokines:___,___
major role in antigen presentation

Answer 24

CD11b+ CD14-
monocyte marker
TNF alpha, Il-6

Question 25

other-antigen presenting cells:macrophages

express low___
inducable by___
present antigen to CD__cytotoxic T cells

Answer 25

HLA IFNy
CD8+

Question 26

other-antigen presenting cells:B-cells

high___inducible by__
presents antigen to CD____helper cells

Answer 26

HLA Il-4
CD4+ T-helper cells

Question 27

other antigen-presenting cells:vascular endothelial cells

low__ inducable by__

Answer 27

HLA IFNy

Question 28

TNF and IL-1 are____cytokineses

Answer 28

preinflammatory