Innate immunity intro Flashcards

Y2C1 1 question will be asked

1
Q

Adaptive immunity mediated by ?

A

lymphocytes

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2
Q

____cells includes,macrophages,mast and dendric cells which initiate immune responses

A

Tissue-resisdent sentinel

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3
Q

Inflammation is also a response for_____cells and accumulation of abnormal substances in tissues even absence of infection

A

dead or damaged

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4
Q

Antiviral defens helps to eliminate viral infection reservoirs without triggering an_________

A

Inflammation

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5
Q

recognition of normal self and nonself in innate immunity is made by expression of molecules that prevent_____reactions

A

Innate immune response

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6
Q

recognition of normal self or nonself in adaptive immunity based on selection aganist______lymphocytes

A

self-reactive

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7
Q

extracellular receptors in innate immunity are
____receptors(TLRs)
____receptors(CLRs)

A

Toll-like
C-type lectin receptors

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8
Q

some TLRs found in______, where they detect nucleic acids of ingested______

A

endosomal
microbes

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9
Q

cytosolic receptors of Innate Immunity are
_____receptors(NLRs)
_____receptors(RLRs)
_____Sensors(CDSs)

A

NOD-like
RIG-like
cytosolic DNA

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10
Q

_____receptors play a role in directing leukocyte migration in response to bacterial signals

A

formylpeptide

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11
Q

Epithelia serve as_____barriers to prevent_____entry

A

physical
microbial

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12
Q

Phagocytes engulf and destroy______&______

A

pathogens & debris

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13
Q

Dendric cells act as______presenting cells that initiate_______immune responses

A

antigen presenting
adaptive

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14
Q

Natural killer cells recognise and kill______infected cells and certain____cells

A

virus-infected
tumor cells

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15
Q

Cytokines small signaling proteins released by cells that mediate and regulate______,_____and_______

A

immunity,inflammatiion and hematopoiesis

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16
Q

Plasma proteins ıncludes complement system proteins that assist in destroying______

A

pathogens

17
Q

epithelial cells produce____antibiotics,such as defensins and cathelicidins

A

peptide antibiotics

18
Q

peptide antibiotics produced by epithelial cells are ?

A

defensins and cathelicidins

19
Q

Epithelia contain________T lymphocytes that recognize microbial___and other microbial structures

A

intraepithelial
lipids

20
Q

neutrophils also known as______nuclear leukocytes(PMNs)

A

polymorphonuclear

21
Q

cytokines known as_____factors(CSFs) induces neutrophil production duing infections

A

colony-stimulating

22
Q

monocytes migrate to tissues and differentiate into?

A

macrophages

23
Q

macrophages/monocytes can produce_____to regulate inflammation

A

cytokines

24
Q

dendric cells respond to mictobes by producing variety of ?

A

cytokines

25
Q

dendritic cells act as bridge between_____&_______

A

Innate & active immunity

26
Q

activation of mast cells occurs by microbial products binding to______receptors as part of_____immunity

A

Toll-like
Innate

27
Q

mast cells secreate_____such as_____factor(TNF)

A

cytokines
tumor necrosis

28
Q

Innate lymphoid cells are_____like cells that produce______and perform similar to__lymphocytes

A

lymphocyte-like
cytokines
T lymphocytes

29
Q

Innate lymphoid cells do not express_____receptors(TCRs)

A

T cell antigen receptors

30
Q

natural killer cells-I secrete____activating cytokine IFN-y

A

macrophage

31
Q

Natural killer cells-I express unique surface____but do not express____or____receptors

A

proteins
immunoglobins
T cell receptors

32
Q

healthly host cells express self class I MHC molecules, which are recognized by_______receptors

A

NK cell inhibitory cells

33
Q

Infected cells get killed by NK cell due to low expression of______molecules which reduces activity of_______

A

Class I MHC molecules
inhibitory receptors

34
Q
A