Innate immunity intro Flashcards
Y2C1 1 question will be asked
Adaptive immunity mediated by ?
lymphocytes
____cells includes,macrophages,mast and dendric cells which initiate immune responses
Tissue-resisdent sentinel
Inflammation is also a response for_____cells and accumulation of abnormal substances in tissues even absence of infection
dead or damaged
Antiviral defens helps to eliminate viral infection reservoirs without triggering an_________
Inflammation
recognition of normal self and nonself in innate immunity is made by expression of molecules that prevent_____reactions
Innate immune response
recognition of normal self or nonself in adaptive immunity based on selection aganist______lymphocytes
self-reactive
extracellular receptors in innate immunity are
____receptors(TLRs)
____receptors(CLRs)
Toll-like
C-type lectin receptors
some TLRs found in______, where they detect nucleic acids of ingested______
endosomal
microbes
cytosolic receptors of Innate Immunity are
_____receptors(NLRs)
_____receptors(RLRs)
_____Sensors(CDSs)
NOD-like
RIG-like
cytosolic DNA
_____receptors play a role in directing leukocyte migration in response to bacterial signals
formylpeptide
Epithelia serve as_____barriers to prevent_____entry
physical
microbial
Phagocytes engulf and destroy______&______
pathogens & debris
Dendric cells act as______presenting cells that initiate_______immune responses
antigen presenting
adaptive
Natural killer cells recognise and kill______infected cells and certain____cells
virus-infected
tumor cells
Cytokines small signaling proteins released by cells that mediate and regulate______,_____and_______
immunity,inflammatiion and hematopoiesis