Innate immunity intro

Question 1

Adaptive immunity mediated by ?

Answer 1

lymphocytes

Question 2

____cells includes,macrophages,mast and dendric cells which initiate immune responses

Answer 2

Tissue-resisdent sentinel

Question 3

Inflammation is also a response for_____cells and accumulation of abnormal substances in tissues even absence of infection

Answer 3

dead or damaged

Question 4

Antiviral defens helps to eliminate viral infection reservoirs without triggering an_________

Answer 4

Inflammation

Question 5

recognition of normal self and nonself in innate immunity is made by expression of molecules that prevent_____reactions

Answer 5

Innate immune response

Question 6

recognition of normal self or nonself in adaptive immunity based on selection aganist______lymphocytes

Answer 6

self-reactive

Question 7

extracellular receptors in innate immunity are
____receptors(TLRs)
____receptors(CLRs)

Answer 7

Toll-like
C-type lectin receptors

Question 8

some TLRs found in______, where they detect nucleic acids of ingested______

Answer 8

endosomal
microbes

Question 9

cytosolic receptors of Innate Immunity are
_____receptors(NLRs)
_____receptors(RLRs)
_____Sensors(CDSs)

Answer 9

NOD-like
RIG-like
cytosolic DNA

Question 10

_____receptors play a role in directing leukocyte migration in response to bacterial signals

Answer 10

formylpeptide

Question 11

Epithelia serve as_____barriers to prevent_____entry

Answer 11

physical
microbial

Question 12

Phagocytes engulf and destroy______&______

Answer 12

pathogens & debris

Question 13

Dendric cells act as______presenting cells that initiate_______immune responses

Answer 13

antigen presenting
adaptive

Question 14

Natural killer cells recognise and kill______infected cells and certain____cells

Answer 14

virus-infected
tumor cells

Question 15

Cytokines small signaling proteins released by cells that mediate and regulate______,_____and_______

Answer 15

immunity,inflammatiion and hematopoiesis

Question 16

Plasma proteins ıncludes complement system proteins that assist in destroying______

Answer 16

pathogens

Question 17

epithelial cells produce____antibiotics,such as defensins and cathelicidins

Answer 17

peptide antibiotics

Question 18

peptide antibiotics produced by epithelial cells are ?

Answer 18

defensins and cathelicidins

Question 19

Epithelia contain________T lymphocytes that recognize microbial___and other microbial structures

Answer 19

intraepithelial
lipids

Question 20

neutrophils also known as______nuclear leukocytes(PMNs)

Answer 20

polymorphonuclear

Question 21

cytokines known as_____factors(CSFs) induces neutrophil production duing infections

Answer 21

colony-stimulating

Question 22

monocytes migrate to tissues and differentiate into?

Answer 22

macrophages

Question 23

macrophages/monocytes can produce_____to regulate inflammation

Answer 23

cytokines

Question 24

dendric cells respond to mictobes by producing variety of ?

Answer 24

cytokines

Question 25

dendritic cells act as bridge between_____&_______

Answer 25

Innate & active immunity

Question 26

activation of mast cells occurs by microbial products binding to______receptors as part of_____immunity

Answer 26

Toll-like
Innate

Question 27

mast cells secreate_____such as_____factor(TNF)

Answer 27

cytokines
tumor necrosis

Question 28

Innate lymphoid cells are_____like cells that produce______and perform similar to__lymphocytes

Answer 28

lymphocyte-like
cytokines
T lymphocytes

Question 29

Innate lymphoid cells do not express_____receptors(TCRs)

Answer 29

T cell antigen receptors

Question 30

natural killer cells-I secrete____activating cytokine IFN-y

Answer 30

macrophage

Question 31

Natural killer cells-I express unique surface____but do not express____or____receptors

Answer 31

proteins
immunoglobins
T cell receptors

Question 32

healthly host cells express self class I MHC molecules, which are recognized by_______receptors

Answer 32

NK cell inhibitory cells

Question 33

Infected cells get killed by NK cell due to low expression of______molecules which reduces activity of_______

Answer 33

Class I MHC molecules
inhibitory receptors