Innate Immunity Flashcards
Define autoimmunity.
The immune system recognises self cells as infectious and destroys them.
Give the two detrimental effects of the immune system.
Inflammation and autoimmunity
What are the key differences between innate and adaptive immunity?
Innate= activated first, rapidly evoked without the need for a signal and non-specific. Adaptive= slow activation, specific, memory cells.
List the 4 mechanisms of innate immunity.
- Anatomical resisting barriers eg skin and mucous
- Physiological barriers eg temperature and pH
- Phagocytosis
- Inflammatory defensive barriers eg vasodilation which increases capillary permeability leading to an influx of phagocytes
True or false, myeloid cells are part of the innate immune system?
True
Give 3 examples of granulocytic myeloid cells.
Neutrophils, basophils and eosinophils
What is the function of granulocytic myeloid cells?
Contain granules which have cytotoxic compounds in which are secreted when in contact with a pathogen.
Give an example of a monocytic myeloid cell.
Macrophages
Which branch of the immune system are lymphoid cells (T and B cells) involved in?
Adaptive immunity
What type of cell is an antigen presenting cell?
A macrophage
What is the most important cellular component in bacterial destruction?
Neutrophils
True or false, neutrophils are the most abundant white blood cells?
True
Which cells are characterised by deep violet-blue granules?
Basophils
Which cells are active in an allergic reaction and release histamine?
Basophils
Which cells have an important role in parasitic infections?
Eosinophils
