Injectible Anesthetics - Cyclohexamines Flashcards
Cyclohexamines are also known as what?
- Dissociogenic agents
What is the parent compound of this class?
- Phencyclidine (PCP)
What are two examples of this class?
- Ketamine hydrochloride
- Tiletamine hydrochloride
What schedule drugs is this class?
- Schedule 3
How does this class work?
- Selective CNS stimulation causing the animal to be awake but unaware (Catalepsy)
What ten aspects of the patient are effected by these classes of drugs?
- Reflexes
- CNS sensitivity
- Muscle tone
- Analgesia
- Psychosomatic
- Respiratory system
- Cardiovascular system
- Kidneys and liver
- Salivary glands
- Eyes
What are the reflex effects of this drug?
- The palpebral, laryngeal, and pharyngeal reflexes are present (Blink and Swallow)
Because of its CNS effects, these drugs are not given to patients with ________.
- Seizures
Describe the muscle tone of patients given these drugs.
- Increasingly rigid
This class has good ______ but bad ________ analgesia.
Peripheral; Visceral
How is the respiratory system effected?
- Apneustic breathing or hyperpnea
How is the cardiovascular system effects?
- Increased HR
- Increased BP
- Decreased contractility`
Because of the cardiovascular effects, what two side effects may occur in patients with cardiac disease?
- Pulmonary edema
- Acute heart failure
This class is metabolized by the liver in the ________ an excreted in the kidneys. It is unchanged in the _____.
Dog; cat
What two types of diseases might cause these drug to have altered duration?
- Renal
- Hepatic