Inhibitors of Cholesterol Absorption Flashcards
1
Q
When is Ezetimibe contraindicated?
A
Breast feeding females
2
Q
What protein does ezetimibe inhibit?
A
Neiman-Pick C1 transport protein
3
Q
What do bile acid binding resins do?
A
Cause excretion of bile salts, resulting in more cholesterol to be converted to bile salts
4
Q
What are the adverse effects of Bile acid binding resins?
A
GI tract irritation
5
Q
What happens to LDL receptor expression in bile acid binding resins?
A
Increases