inhertitence Flashcards
genotype
genetic constitution of an organism
phenotype
the expression of the genotype and its interactions with the environment
alleles
variant of a particular gene
what causes multiple alleles
occurs due to mutations in a gene that occur at different position in a gene
homozygotes
same type of allele
heterozygous
both alleles are different
dominant
expressed in the phenotype of a heterozygote, only 1 copy needed for expression
recessive
not expressed in the phenotype of a heterozygote, so 2 copies are needed for expression
codominant alleles
equally dominant and equally expressed in phenotype e.g. blood type AB
monohybrid cross
used to predict outcome of 2 different genotypes
what is the layout of a monohybrid cross
- parental genotype
- Gametes
3: cross
Test crosses
used to determine unknown genotype
unknown genotype crosses with homozygous recessive individual
if all offspring have dominant phenotype - genotype is homozygous dominant
if half offspring have recessive phonotype the unknown is heterozygous
dihybrid cross
inheritance of 2 different genes
autosomal linkage
tow or more genes located on the same autosome
how does autosomal linked genes inherited together and why (not)?
less likely to be seperated during crossing over so are inherited together
how does autosomal linkage affect the offspring genotype
offspring more likely to resemble parental genotype, effects ratio
sex linkage
gene is on X chromosome (or Y)
how does this affect inheritance of genes in offspring?
males more likely to inherit recessive condition as only require 1 copy for it to be expressed in the phenotype (as males only have 1 X)
epistasis
interaction between 2 genes where one gene masks the expression of the other gene in the phenotype
what is the gene that supressed the gene called
epistatic gene
what is the gene that’s being repressed by the epistatic gene called
hypostatic gene
can epistatic interaction be dominant or recessive?
yes, both
chi squared test
determines the probability of an unexpected result being due to chance or being significant
what is the null hypothesis
any difference that occurs between observed and expected results is due to chance