inheritance, variation and evolution Flashcards
Types of Cell Division:
Types of Cell Division:
Mitosis
Meiosis
what are gametes and what are some examples?
gametes are sex cells e.g. egg/sperm cell, pollen
In sexual reproduction, male and female gametes _____.
In sexual reproduction, male and female gametes fuse.
Mitosis
Two genetically ________ daughter cells
Meiosis
____ genetically __________ daughter cells
Mitosis
Two genetically identical daughter cells
Meiosis
Four genetically non-identical daughter cells
Asexual reproduction
Asexual reproduction
Divide by mitosis
No gamete fusion
One parent
Offspring are clones
Asexual reproduction is common in …?
Asexual reproduction is common in single-celled organisms(e.g. bacteria) and some plants.
Division of cells by meiosis (or meiotic division) in reproductive organs produces _______ with ____ the number of chromosomes found in all other body ____.
Division of cells by meiosis (or meiotic division) in reproductive organs produces gametes with half the number of chromosomes found in all other body cells.
stages of meiosis
Cells split
Each cell has a pair of each chromosome (diploid cell).
During meiosis each pair of chromosomes replicate and the cell splits in two.
Further cell splitting
There are now two identical cells.
The diploid cell divides again.
Haploid cells created
This creates four genetically different gametes that each have half the number of chromosomes of the parent cell. Cells that have only one copy of each chromosome (such as gametes) are called haploid cells.
Gametes fertilise
During sexual reproduction, the male gamete fertilises the female gamete and the fertilised cell now has the normal number of chromosomes (46 in humans).
Mitosis
Once the gametes have combined, the new cell divides by mitosis (the cell grows asexually).
As soon as the embryo reaches a certain size, cells begin to differentiate (specialise).
what can sometimes reproduce both sexually and asexually:
what can sometimes reproduce both sexually and asexually:
1 Fungi 2 Malaria parasites 3 Strawberry plants
An advantage of sexual reproduction is …
An advantage of sexual reproduction is variation in the offspring, increasing the chances of a population being able to survive environmental change by natural selection.
If an organism can reproduce sexually or asexually, it often reproduces _______ when conditions are good.
If an organism can reproduce sexually or asexually, it often reproduces asexually when conditions are good.
asexual reproduction is _______ than sexual reproduction
asexual reproduction is faster than sexual reproduction
What are the 4 genetically different gametes produced during sexual reproduction called?
What are the 4 genetically different gametes produced during sexual reproduction called?
haploid cells
The three levels of organisation of a genome:
The three levels of organisation of a genome:
DNA (smallest)
genes
chromosomes (biggest)
The genome is the entire (all) genetic ________ of an organism.
The genome is the entire (all) genetic material of an organism.
The nucleus of eukaryotic cells contains chromosomes made of DNA _________.
Each chromosome contains a large number of _____.
Each gene tells how a specific _______ should be made.
The nucleus of eukaryotic cells contains chromosomes made of DNA molecules.
Each chromosome contains a large number of genes.
Each gene tells how a specific protein should be made.
Contain lots of genes.
The human body contains 23 pairs of these and one of each pair comes from each parent.
Chromosomes
Chromosomes contain lots of genes. The human body contains 23 pairs of chromosomes and one of each pair comes from each parent.
This is a small section of DNA.
They code for a sequence of amino acids, which combine to make a specific protein.
Gene
a gene is a small section of DNA. genes code for a sequence of amino acids, which combine to make a specific protein.
This is a polymer (a chemical made by taking a group of molecules and repeating them many times) made up of two strands forming a double helix shape.
DNA is double helix polymer, which means it is a polymer (a large molecule made up of many subunits) made up of two strands forming a twisted, ladder shape.
A gene is a _____ of DNA. There are about 300 genes in the smallest human chromosome.
A gene is a segment of DNA. There are about 300 genes in the smallest human chromosome.
When was the Human Genome Project completed?
2003
Genome sequencing may help us to identify and cure _____ diseases in the future.
Genome sequencing may help us to identify and cure genetic diseases in the future.
How could the completion of the Human Genome Project, and subsequent research on the human genome, be beneficial in tackling Cystic Fibrosis?
How could the completion of the Human Genome Project, and subsequent research on the human genome, be beneficial in tackling Cystic Fibrosis?
The knowledge we have gained from the Human Genome Project and subsequent research can help us in identifying Cystic Fibrosis genes, allowing those carrying it to be made aware.
It could also further our understanding of the disorder and how we should be treating it.
The Human Genome Project has advanced our knowledge, which should lead to … (3)
better investigations into human evolutionary history
identification of genes linked to disorders
improved understanding of inherited disorders
Protein synthesis is …
Protein synthesis is how our bodies make proteins.
Each amino acid is coded for by a specific sequence of three bases, called a ______.
The order of the bases on the DNA impacts the order in which amino acids are combined to form _______.
Changing the sequence of bases can change the ______ made by a gene.
Each amino acid is coded for by a specific sequence of three bases, called a codon.
The order of the bases on the DNA impacts the order in which amino acids are combined to form proteins.
Changing the sequence of bases can change the protein made by a gene.
During protein synthesis, specific amino acids are delivered by _________ molecules to the protein chain.
During protein synthesis, specific amino acids are delivered by carrier molecules to the protein chain
If the order of bases on DNA changes, what happens to the proteins made using the DNA?
the amino acid sequence may change
stages of protein synthesis
a template is taken from the DNA and leaves the nucleus
the template is used to guide protein synthesis on ribosomes located in the cytoplasm
specific amino acids are delivered by carrier molecules to the protein chain, where they are added in the order shown on the template
once completed the long protein chain molecule folds up giving it a unique structure
A mutation is a change in the _________ sequence of DNA.
A mutation is a change in the nucleotide sequence of DNA.
__________ is often disadvantageous, but can bring advantages (a mutation may give a survival advantage, such as resistance to an antibiotic in bacteria.)
mutations is often disadvantageous, but can bring advantages (a mutation may give a survival advantage, such as resistance to an antibiotic in bacteria.)
In most cases, a characteristic results from ________ genes interacting.
However, sometimes, a single gene is responsible for a characteristic. such as red-green colour ________.
In most cases, a characteristic results from multiple genes interacting.
However, sometimes, a single gene is responsible for a characteristic. such as red-green colour blindness.
If an individual possesses the genotype BB, we would say they were:
If an individual possesses the genotype BB, we would say they were:
homozygous
dominant
If a person has two alleles the same, we say that they are:
If a person has two alleles the same, we say that they are:
homozygous
If the allele for a free earlobe is E (dominant) and the allele for an attached earlobe is e (recessive), what will the earlobe of a person with the genotype Ee be like?
If the allele for a free earlobe is E (dominant) and the allele for an attached earlobe is e (recessive), what will the earlobe of a person with the genotype Ee be like?
The person is heterozygous.
This means that the dominant trait will be observed, and so their earlobe will be free. This assumes that the environment has not interfered.
A ________ allele is always expressed, regardless of what the other allele is. It only needs one copy to be expressed (to be in) a person.
A dominant allele is always expressed, regardless of what the other allele is. It only needs one copy to be expressed (to be in) a person.
Some regions of DNA do not _______ protein sequences.
The term given to these sections is non-coding DNA.
Non-coding DNA often plays a role in gene __________.
Therefore, mutations that arise here may result in genes being switched on or off.
Some regions of DNA do not encode protein sequences.
The term given to these sections is non-coding DNA.
Non-coding DNA often plays a role in gene expression.
Therefore, mutations that arise here may result in genes being switched on or off.
Cystic fibrosis is a disorder of cell _________.
It is caused by a ________ allele.
Cystic fibrosis causes thick, sticky mucus to build-up in the ____ and digestive system.
Cystic fibrosis is a disorder of cell membrane.
It is caused by a recessive allele.
Cystic fibrosis causes thick, sticky mucus to build-up in the lungs and digestive system.
If a sufferer of cystic fibrosis has non-suffering parents, what are the parents?
If a sufferer of cystic fibrosis has non-suffering parents, what are the parents?
heterozygotes
People can now have their ________ screened to look for genes that cause the individual to be more susceptible to genetic disorders.
People can now have their genome screened to look for genes that cause the individual to be more susceptible to genetic disorders.