Inheritance Of Blood Groups Flashcards

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1
Q

how many potential blood types do humans have and what are they

A
  • humans have 4 potential blood group types

- they are a, o, b and ab

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2
Q

how many different alleles can the gene for blood type have and what are they

A
  • there are 3 different alleles

- they are Ia Ib and Io

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3
Q

what is the relationship between la and lb alleles

A

they are co dominant with each other

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4
Q

what does the co dominance between alleles la and lb mean if an individual inherits them

A

when someone has both of those alleles (genotype la and lb) they will have the blood type ab

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5
Q

what does co dominant mean

A

that one allele isnt dominant over the other one

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6
Q

which allele responsible for blood type is recessive

A

lo

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7
Q

what blood type would you get if you were to have in individual with an lo and la genotype

A

if someone had the genotype of lo,la you would only see the effect of la because la is dominant over lo (lo is recessive)
- so their blood type would be a

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8
Q

when would someone have the blood type of o

A

if they had two of the recessive alleles, lo lo

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9
Q

what is different when drawing a genetic diagram for blood type compared to other factors such as sex

A
  • when you have worked out the potential genotypes, predicting the potential phenotypes is harder
  • because you need to remember how the different alleles of blood type interact with each other, like co dominance
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10
Q

what would be the phenotype of a man with the genotype la lo

A
  • the la is dominant over the lo
  • they are different alleles
  • so his phenotype is heterozygous blood group a
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11
Q

what would be the phenotype of a woman with the genotype lb lo

A
  • the lb is dominant over the lo
  • they are different alleles
  • so her phenotype is heterozygous blood group b
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12
Q

if a man with the phenotype of heterozygous blood group a and a woman with the phentype heterozygous blood group b were to have off spring, what would be punnett square of their different genotype possibilities look like

A
  • man is heterozygous blood group a
  • woman is heterozygous blood group b
  • meaning man has gentype of la lo
  • meaning woman has gentype of lb lo
  • combinations of gametes alleles are:
  • la lb (group ab)
  • la lo (group a)
  • lo lb (group b)
  • lo lo (group o)
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13
Q

if a man with the genotype la lo and a woman with the gentype lb lo were to have off spring what would be chances of the child having one of the four blood groups

A
  • the child could have any one of the four different blood groups
  • so the child had an equal chance (25% or 1 in 4 chance) of having each blood group
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14
Q

why is someone with the blood type o so rare

A

because the allele coding for the blood type (lo) is recessive and is usually dominated by the other alleles la and lb

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